Recent advances in molecular targets and treatment of idiopathic pulmonary fibrosis: focus on TGFbeta signaling and the myofibroblast
Defective histone acetylation is responsible for the diminished expression of cyclooxygenase 2 in idiopathic pulmonary fibrosis
y-Herpes virus-68, but not Pseudomonas aeruginosa or influenza A (H1N1), exacerbates established murine lung fibrosis
Microarray identifies ADAM family members as key responders to TGF-beta1 in alveolar epithelial cells
Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties
Targeting genes for treatment in idiopathic pulmonary fibrosis: challenges and opportunities, promises and pitfalls
Th1/Th2 cytokine gene polymorphisms in patients with idiopathic pulmonary fibrosis
VCAM-1 is a TGF-b1 inducible gene upregulated in idiopathic pulmonary fibrosis
Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis
Combined inhibition of TGFb and PDGF signaling attenuates radiation-induced pulmonary fibrosis
Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-kB in mice
Carbon monoxide-bound hemoglobin-vesicles for the treatment of bleomycin-induced pulmonary fibrosis
Regulation of TGF-b storage and activation in the human idiopathic pulmonary fibrosis lung
Prognostic factors for idiopathic pulmonary fibrosis: clinical, physiologic, pathologic, and molecular aspects
Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF
Association of HLA and cytokine gene polymorphisms with idiopathic pulmonary fibrosis
Oxidant-antioxidant imbalance as a potential contributor to the progression of human pulmonary fibrosis
A translational preclinical model of interstitial pulmonary fibrosis and pulmonary hypertension: mechanistic pathways driving disease pathophysiology
Pirfenidone for the treatment of idiopathic pulmonary fibrosis
Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis
Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-b signaling
Blockade of the Wnt/b-catenin pathway attenuates bleomycin-induced pulmonary fibrosis
Epithelial stem cell exhaustion in the pathogenesis of idiopathic pulmonary fibrosis
Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis
Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis
Pigment epithelium-derived factor in idiopathic pulmonary fibrosis: a role in aberrant angiogenesis
Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis
Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention
Signaling pathways and their miRNA regulators involved in the etiopathology of idiopathic pulmonary fibrosis (IPF) and hypersensitivity pneumonitis (HP)
Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis
Inhibitory effects of amines from Citrus reticulata on bleomycin-induced pulmonary fibrosis in rats
Beyond TGFb - Novel ways to target airway and parenchymal fibrosis
Elevated sL1-CAM levels in BALF and serum of IPF patients
The potential application of strategic released apigenin from polymeric carrier in pulmonary fibrosis
Epithelial contribution to the pro-fibrotic stiff microenvironment and myofibroblast population in lung fibrosis
Release of biologically active TGF-beta1 by alveolar epithelial cells results in pulmonary fibrosis
Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis
Thalidomide reduces IL-18, IL-8 and TNF-alpha release from alveolar macrophages in interstitial lung disease
Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension
Corilagin attenuates aerosol bleomycin-induced experimental lung injury
Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease
Angiotensin-TGF-beta 1 crosstalk in human idiopathic pulmonary fibrosis: autocrine mechanisms in myofibroblasts and macrophages
Increased expression of protease nexin-1 in fibroblasts during idiopathic pulmonary fibrosis regulates thrombin activity and fibronectin expression
Plasma CCN2 (connective tissue growth factor; CTGF) is a potential biomarker in idiopathic pulmonary fibrosis (IPF)
Microencapsulation of lefty-secreting engineered cells for pulmonary fibrosis therapy in mice
p63 - Key molecule in the early phase of epithelial abnormality in idiopathic pulmonary fibrosis
Increased interleukin-1 receptor antagonist in idiopathic pulmonary fibrosis
Molecular pathogenesis of interstitial pneumonitis with TNF-alpha transgenic mice
Bleomycin in the setting of lung fibrosis induction: From biological mechanisms to counteractions
Antifibrotic properties of receptor for advanced glycation end products in idiopathic pulmonary fibrosis
Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis
Immunoglobulin A in serum: an old acquaintance as a new prognostic biomarker in idiopathic pulmonary fibrosis
Defect of hepatocyte growth factor secretion by fibroblasts in idiopathic pulmonary fibrosis
Possible involvement of pirfenidone metabolites in the antifibrotic action of a therapy for idiopathic pulmonary fibrosis
BAX inhibitor-1-associated V-ATPase glycosylation enhances collagen degradation in pulmonary fibrosis
Idiopathic pulmonary fibrosis: pathobiology of novel approaches to treatment
Novel pharmacological approaches to manage interstitial lung fibrosis in the twenty-first century
IL-4 polymorphisms, HRCT score and lung tissue markers in idiopathic pulmonary fibrosis
Effects of antifibrotic agents on TGF-beta1, CTGF and IFN-gamma expression in patients with idiopathic pulmonary fibrosis
[The expressions and meanings of BMP-7 and TGF-b in idiopathic pulmonary fibrosis and idiopathic nonspecific interstitial pneumonia]
Increased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of b1,3-glucuronosyltransferase I in pulmonary fibrosis
Discovery and validation of extracellular/circulating microRNAs during idiopathic pulmonary fibrosis disease progression
TGF-b1 T869C polymorphism may affect susceptibility to idiopathic pulmonary fibrosis and disease severity
Medical treatment for pulmonary fibrosis: current trends, concepts, and prospects
Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis
Comparison between conventional and "clinical" assessment of experimental lung fibrosis
Intratracheal bleomycin causes airway remodeling and airflow obstruction in mice
Role of endoplasmic reticulum stress in age-related susceptibility to lung fibrosis
Transforming growth factor b1 (TGFb1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis
Increased levels of prostaglandin E-major urinary metabolite (PGE-MUM) in chronic fibrosing interstitial pneumonia
Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis
Modulation of CD11c+ lung dendritic cells in respect to TGF-b in experimental pulmonary fibrosis
Expression of suppressor of cytokine signaling 1 in the peripheral blood of patients with idiopathic pulmonary fibrosis
Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts
Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis
Raised serum levels of IGFBP-1 and IGFBP-2 in idiopathic pulmonary fibrosis
Inhibition of NF-kappaB signaling reduces virus load and gammaherpesvirus-induced pulmonary fibrosis
N-acetylcysteine downregulation of lysyl oxidase activity alleviating bleomycin-induced pulmonary fibrosis in rats
Cytokine gene polymorphisms and BALF cytokine levels in interstitial lung diseases
Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models
JAK2 mediates lung fibrosis, pulmonary vascular remodelling and hypertension in idiopathic pulmonary fibrosis: an experimental study
Ambroxol hydrochloride in the management of idiopathic pulmonary fibrosis: Clinical trials are the need of the hour
IL-17A deficiency mitigates bleomycin-induced complement activation during lung fibrosis
TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease
Pleural mesothelial cell differentiation and invasion in fibrogenic lung injury
Signalling pathways from NADPH oxidase-4 to idiopathic pulmonary fibrosis
Association between cytokine removal by polymyxin B hemoperfusion and improved pulmonary oxygenation in patients with acute exacerbation of idiopathic pulmonary fibrosis
Overexpression of squamous cell carcinoma antigen in idiopathic pulmonary fibrosis: clinicopathological correlations
Intrinsic defence capacity and therapeutic potential of natriuretic peptides in pulmonary hypertension associated with lung fibrosis
Microsomal prostaglandin E synthase-1 deficiency exacerbates pulmonary fibrosis induced by bleomycin in mice
Preventive and therapeutic effects of thymosin b4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis
Serpin B4 isoform overexpression is associated with aberrant epithelial proliferation and lung cancer in idiopathic pulmonary fibrosis
Dehydroepiandrosterone has strong antifibrotic effects and is decreased in idiopathic pulmonary fibrosis
Establishment of the mouse model of acute exacerbation of idiopathic pulmonary fibrosis
Spiruchostatin A inhibits proliferation and differentiation of fibroblasts from patients with pulmonary fibrosis
Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis
Tumor necrosis factor superfamily 14 (LIGHT) controls thymic stromal lymphopoietin to drive pulmonary fibrosis
High levels of IL-6 and IL-8 characterize early-on idiopathic pulmonary fibrosis acute exacerbations
Defect of pro-hepatocyte growth factor activation by fibroblasts in idiopathic pulmonary fibrosis
Lung infection with gamma-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice
Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium
Cytokine gene polymorphisms and serum cytokine levels in patients with idiopathic pulmonary fibrosis
Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice
Reduced expression of BMP3 contributes to the development of pulmonary fibrosis and predicts the unfavorable prognosis in IIP patients
The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis
The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis
An inhibitor of NADPH oxidase-4 attenuates established pulmonary fibrosis in a rodent disease model
Peripheral depletion of NK cells and imbalance of the Treg/Th17 axis in idiopathic pulmonary fibrosis patients
Bone morphogenetic protein-4 inhibitor gremlin is overexpressed in idiopathic pulmonary fibrosis
Role of protease-activated receptor-2 in idiopathic pulmonary fibrosis
Type V collagen induced tolerance suppresses collagen deposition, TGF-b and associated transcripts in pulmonary fibrosis
Extracellular superoxide dismutase has a highly specific localization in idiopathic pulmonary fibrosis/usual interstitial pneumonia
Effects of the tumor suppressor PTEN on the pathogenesis of idiopathic pulmonary fibrosis in Chinese patients
The impact of TGF-b on lung fibrosis: from targeting to biomarkers
Herpes virus infection is associated with vascular remodeling and pulmonary hypertension in idiopathic pulmonary fibrosis
Recombinant human serum amyloid P in healthy volunteers and patients with pulmonary fibrosis
Alveolar epithelial cell injury with Epstein-Barr virus upregulates TGFbeta1 expression
Nuclear factor erythroid 2-related factor 2 nuclear translocation induces myofibroblastic dedifferentiation in idiopathic pulmonary fibrosis
Activated MCTC mast cells infiltrate diseased lung areas in cystic fibrosis and idiopathic pulmonary fibrosis
Crosstalk between TGF-b1 and complement activation augments epithelial injury in pulmonary fibrosis
Age-driven developmental drift in the pathogenesis of idiopathic pulmonary fibrosis
Current and novel drug therapies for idiopathic pulmonary fibrosis
Reduced transcription of the Smad4 gene during pulmonary carcinogenesis in idiopathic pulmonary fibrosis
Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis
Data on CUX1 isoforms in idiopathic pulmonary fibrosis lung and systemic sclerosis skin tissue sections