Update README.md

 # MONOGENIC DISEASES
 # MONOGENIC DISEASES
-## Human Genomics
+## Human Genomics Project
 
 
 Team:
 Team:
 - Garcia Flores Fernanda Renee
 - Garcia Flores Fernanda Renee
@@ -8,5 +8,32 @@ Team:
 - Zeferino Garcia Karla 
 - Zeferino Garcia Karla 
 
 
 Here we display all the data and scripts used in order to answer one of the most relevant actual questions in the field of Human Health:  
 Here we display all the data and scripts used in order to answer one of the most relevant actual questions in the field of Human Health:  
+**Which is the proportion of diseases that are caused due to afections in coding and non coding regions?**  
 
 
-**Which is the proportion of diseases that are caused due to afections in coding and non coding regions?**
\ No newline at end of file
+## Folder content  
+- *alignments*  
+    Contains the resultant files of aligning the secuences from genes of interest (that cause a monogenis disease) to the human genome.
+    - sequences_aligned_A.bam
+    - sequences_aligned_A.sam
+    - sequences_aligned_A_sort.bam
+- *data*
+    - *DISEASES DB*  
+        Stores one of the databases use for the project and a file that has all the information of the monogenic diseases contained within it.
+        - human_disease_textmining_full.tsv 
+        - merge_list_monogenic_diseases.tsv
+        - merge_monogenic_diseases.tsv
+    - *Ensembl*  
+        Harbors information about human genes.
+        - mart_export_v2.txt
+    - *Homo_sapiens*  
+        Includes human genome sequence and it's annotation.
+        - Homo_sapiens.GRCh38.100.gff3.gz
+        - Homo_sapiens.GRCh38.dna.alt.fa.gz
+    - *OMIM*  
+        Contains a file that has information about different heritable conditions, and another file has the information that corresponds to monogenic diseases.
+        - genemap2.txt
+- *scripts*  
+    Has the scripts that were used through this project.
+    - ObtencionSecuencias.R
+    - alineamiento.sh
+    - get_monogenic_disease_data.sh