S. Typhi where StpA represses only in an hns background
S. Typhi where StpA represses only in an hns background
Because StpA potentially represses hns , we downregulated in a DstpA strain .
Because StpA potentially represses hns , we expected such genes to be upregulated in an hns mutant .
Point mutations M4T enhance StpA repression of select hns .
Point mutations A77D enhance StpA repression of select hns .
One possibility worth investigating is that the partial repression of the proU operon in media of low osmolality in hns mutants is mediated by the StpA protein .