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We reasoned that because Crl participates in the negative regulation by S , a crl mutant should display a competitive advantage over the wild-type strain .
The finding that the crl mutant had an advantage over the wild-type strain for fitness in stationary-phase indicated that Crl contributes to negative regulation by S .
The finding that the crl mutant had an advantage over the wild-type strain for growth-on-succinate in stationary-phase indicated that Crl contributes to negative regulation by S .