( C ) Alignment of the promoter regions of steA and six PhoP-activated genes with a similar architecture ( 49 ) .
Here , we show that steA possesses a PhoP-activated promoter with a PhoP box located 12 nucleotides upstream of the 10 hexamer , resembling promoters with architecture I .
These results establish that regulation of steA by PhoQ/PhoP suggest that PhoP could be a direct activator of steA .
Results suggest that PhoP could be a direct activator of steA transcription .
that PhoP directly activates steA
A similar motif is found in the promoters of a subset of PhoP-activated genes , including steA , phoP , mgtA , pmrD , slyB , and orgB ( Fig. 6B ) .