Previously , we dem-onstrated that HilD directly induces the expression of the ssrAB operon .
This suggests that HilD induces the expression of ssrAB also by counteracting H-NS-me-diated repression of its promoter .
All together , these results indicate that HilD induces the expression of ssrAB by displacing the H-NS nucleoprotein complex from the promoter of this operon .
Furthermore , our results indicate that HilD induces the expression of ssrAB by binding to one located on .
Furthermore , our results indicate that HilD induces the expression of ssrAB by binding to at least two different AT-rich regions .
Interestingly , when S. Typhimurium is grown to late stationary-phase in LB-medium , HilD directly induces the expression of the ssrAB operon .
HilD can activate the ssrAB operon by specifically interacting with its regulatory region to upregulate SPI-2 .
HilD can also induce expression of SPI-2 by direct binding to the promoter of ssrAB .