However , the Fis-regulated E. coli proP gene seems to be regulated in a manner similar to that of hilA , in that levels are low during early exponential phase growth , followed by a burst of expression in late exponential-growth and a decrease in expression during stationary-phase ( Xu and Johnson , 1995 ) .
In our model , we propose that Fis acts as a positive regulator of hilA .
However , the Fis-regulated E. coli proP gene seems to be regulated in a manner similar to that of hilA , in that levels are low during early exponential phase growth .
Fis is involved in SPI expression Positive regulation of SPI-1 genes by Fis was expected considering the fact that hilA , is upregulated by Fis .
The hilA promoter is directly controlled by Fis .