H-NS , negatively regulates ompS1 expression by binding upstream of position -88 .
Expression of ompS1 was induced in an hns mutant , consistent with the notion that H-NS represses these genes ; transcriptional activity was lower for STY1978 in an hns background , suggesting that this global regulatory protein has a positive effect .
The transcriptional profile was consistent with the hypothesis that H-NS represses the expression of ompS1 , .
The results of our experiments concur with the concept that H-NS represses the expression of ompS1 in Salmonella serovar Typhi .
Previous studies also showed that ompS1 are repressed by H-NS in Salmo-nella serovar Typhimurium .