The distal half of this motif is very similar to the consensus sequence previously defined for a subset of PhoP-regulated genes that contain a promoter pattern known as architecture I ( 48 ) , whereas the other half of the motif is not conserved in slrP .
that PhoP can directly bind to the promoter region of slrP
Direct regulation of slrP expression by PhoP .
The level of expression of the lac fusions indicated that these fragments contained the motifs necessary for PhoP regulation of slrP .
As seen in Fig. 7B , PhoP was able to bind to the promoters of slrP .
FIG 7 PhoP binds to the promoter of slrP .
slot blot-based experiments _ showing binding of PhoP to DNA fragments containing the promoter region of slrP
Similarly , the expression of slrP , also encoding an effector protein , is controlled by the response regulator PhoP in SPI-2-inducing conditions32 .