If a condition exists in which hilA is repressed while invF expression is induced through HilC , it begs the question : Why produce InvF-dependent effectors in the absence of hilA expression when an intact type III secretion apparatus is not thought to be formed ?
Transcriptional activation by HilC relieves repression of the hilA promoter by the nucleoid proteins H-NS and Hha .
In addition , a role of HilC mediated repression of hilA was not investigated .
HilC relieve repression of the hilA promoter by the nucleoid proteins H-NS and Hha .
H-NS repression of hilA counteracts transcriptional activation by HilC