RamA was required for indole induction of acrAB .
Here we report on induction of acrAB in Salmonella via the specific regulator RamA in response to indole .
The results indicate that the RamA regulator is required for indole induction of acrAB in Salmonella .
Requirement of RamA for induction of acrAB by bile .
RamA Binds to the Upstream Regions of tolC -- The aforementioned results indicate that RamA plays a major role in inducing acrAB in response to environmental signals .
RamA Binds to the Upstream Regions of acrA -- The aforementioned results indicate that RamA plays a major role in inducing acrAB in response to environmental signals .
RamA Binds to the Upstream Regions of tolC -- The aforementioned results indicate that RamA plays a major role in inducing acrAB in response to bile .
RamA Binds to the Upstream Regions of tolC -- The aforementioned results indicate that RamA plays a major role in inducing acrAB in response to indole .
RamA Binds to the Upstream Regions of acrA -- The aforementioned results indicate that RamA plays a major role in inducing acrAB in response to bile .
RamA Binds to the Upstream Regions of acrA -- The aforementioned results indicate that RamA plays a major role in inducing acrAB in response to indole .
RamA induction of acrAB by conditioned-medium of E. coli .
We found that acrAB induction by these three signal sources is completely dependent on the Salmonella-specific regulator RamA , indicating that RamA plays a major role in inducing acrAB .
We found that acrAB induction by these three signal sources is completely dependent on the Salmonella-specific regulator RamA , indicating that RamA plays a major role in inducing acrAB .
However , our data indicate that bile induction of acrAB in Salmonella is completely dependent on RamA , not Rob .
The acrAB induction by these three signal sources is completely dependent on the Salmonella-specific regulator RamA , indicating that RamA plays a major role in inducing acrAB .
The acrAB induction by these three signal sources is completely dependent on the Salmonella-specific regulator RamA , indicating that RamA plays a major role in inducing acrAB .
However , our data indicate that bile induction of acrAB in Salmonella is completely dependent on RamA , not Rob .
Our results suggest that RamAmediated acrAB expression is induced either via overexpression of activation of poorly-expressed RamA .
Our results suggest that RamAmediated acrAB expression is induced either via overexpression of a weakly active RamA protein .
In Salmonella , RamA is involved in inducing acrAB in addition to the abovementioned regulators .
via the RamA regulator The induction of acrAB in response to paraquat suggested that this induction mechanism might be mediated by the RamA regulator
acrAB induction by paraquat was observed in the DramA strain , indicating that RamA was not required for this induction response .
RamA directly induces acrAB .
In SI3 , RamA played predominant role in ciprofloxacin resistance via increasing the expression level of acrAB .
Activation of the acrAB operon is achieved through the direct binding of RamA , to the operator regions of these genes .
that acrAB induction by indole is dependent on RamA
that acrAB induction by indole is dependent on RamA
that acrAB induction by indole is dependent on RamA
The acrAB genes are transcriptionally activated by RamA .
As expected , since RamA is PramA , we first conducted EMSAs with a 97 bp transcriptional activator of the acrAB ,18 bile DNA fragment + -- + -- Figu .
As expected , since RamA is PramA , we first conducted EMSAs with a 97 bp transcriptional activator of the acrAB ,18 bile DNA fragment + -- + - + .
As expected , since RamA is the main the ramA promoter , we first conducted EMSAs with a 97 bp transcriptional activator of the acrAB ,18 bile DNA fragment + -- + -- Figu .
As expected , since RamA is the main the ramA promoter , we first conducted EMSAs with a 97 bp transcriptional activator of the acrAB ,18 bile DNA fragment + -- + - + .
RamA plays a key role in increasing the expression level of the efflux pump by binding to the upstream promoter region of acrAB and to .