Furthermore , this indicates that a relA-dependent source of ppGpp can compensate for any leucine-mediated inactivation of Lrp , either through elevated lrp expression or through other ppGpp-dependent mechanisms .
In contrast , the presence of both lrp mutations in the donor strain restored the repression of pSLT transfer to a level similar to that of an Lrp-mutant .
Lrp -- DNA interaction in this region was fully consistent with the observed repression of lrp transcription by this protein .
that Lrp repressed the transcription of the lrp gene
This pattern of protein -- DNA interaction is consistent with repression of the lrp promoter by Lrp promoter occlusion .
lrp expression , is repressed , leading to low levels of Lrp
Lrp represses the expression of an lrp deletion mutant displays hypervirulence .