The S. Typhimurium ferritins are differentially regulated Previous studies in E. coli have shown that Fur positively regulates ftnA expression under Fe-replete conditions .
Thus , ftnA genes are positively regulated by Fe in a Fur-dependent manner , accounting for reduced total Fe in the fur mutant .
Similar to ftnA genes are activated by Fe in a Fur-dependent manner , most likely via Fur-mediated repression of RyhB .
Similar to ftnA genes are activated by Fe in a Fur-dependent manner , most likely via Fur-mediated repression of the small RNA .
In the case of the iron-storage protein ferritin , FtnA , gene expression is induced by Fur with an extended Fur binding site -LRB- containing five tandem Fur boxes -RRB- located upstream of the ftnA promoter .