The SoxRS-and MarRAB-regulated genes that contribute t broad antibiotic resistance include the acrAB operon encoding a multidrug efflux pump ( 22 , 25 , 30 ) and the micF gene encoding an antisense RNA that inhibits synthesis of the OmpF outer membrane porin ( 6 , 7 , 32 ) .
Altogether , these results indicated that lack of AsmA does not increase acrAB transcription and suggested that bile resistance mediated by asmA mutations may involve MarRAB-regulated genes other than acrAB .
Altogether , these results indicated that lack of AsmA does not increase acrAB transcription and suggested that bile resistance mediated by asmA mutations may involve MarRAB-regulated genes other than acrAB .