SirA Orthologs Affect both Motility 43210 The sirA gene of Salmonella enterica serovar Typhimurium encodes a two-component response regulator of the FixJ family .
No further increase in PefA expression was apparent in a sirA csrB csrC DfimAICDHF mutant ( TS133 ) ( Figure 2C ) , thus the lack of SirA or inactivation of the SirA-regulated genes csrB and csrC produced similar effects on PefA expression .