This suggests that HilD induces the expression of ssrAB also by counteracting H-NS-me-diated repression of its promoter .
However , how HilD counteracts the H-NS-mediated repression of ssrAB , or even of other target genes , had not yet been determined .
all the cis elements _ required for the H-NS-mediated repression of ssrAB
Thus , these results indicate that the sequence upstream of position 55 is not required for the H-NS-mediated repression of ssrAB .
multiple cis elements _ required for the H-NS-mediated repression of ssrAB
further _ supporting the role of HilD as an antagonist of H-NS-mediated repression of ssrAB
further _ supporting the role of HilD as an antagonist of H-NS-mediated repression of ssrAB
FIG 4 Analysis of the cis-acting sequences required for the H-NS-mediated repression of ssrAB .
that the sequence upstream of position 55 is not required for the H-NS-mediated repression of ssrAB
that consecutive deletion of the 119/240 regions results in a gradual release of the H-NS-me-diated repression of ssrAB
that consecutive deletion of the 240/336 regions results in a gradual release of the H-NS-me-diated repression of ssrAB
another regulator may act along with HilD to counteract a double mechanism of H-NS-mediated repression of ssrAB
Therefore , SlyA might replace HilD to counteract H-NS-mediated repression of ssrAB when Salmonella is grown in minimal media .
Mechanistically , HilD indirectly regulates SsrB-regulated genes by antagonizing the H-NS-mediated repression of ssrAB at stationary-phase under SPI-1 .