PhoP-regulated genes were further identified by transcriptional profiling using microarrays of strain CS022 containing a phoQ mutation that results in increased expression of PhoP-activated genes and a phoP null mutant ( W.N. , unpubl .
Transcriptional regulation of Salmonella virulence -- a phoQ periplasmic domain mutation results in increased net phosphotransfer to PhoP .
The PhoP/PhoQ system is required for transcription from one of the promoters of the slyA gene ( 20 ) , suggesting that some of the phenotypes displayed phoP and phoQ mutants could be caused by their inability to express the SlyA protein and implying that SlyA participates in transcription of a subset of PhoP-regulated genes .
that harbored a plasmid with the phoQ genes under the control of a derivative of the lac promoter because a strain with a chromosomal phoQ mutation would constitutively activate the PhoP protein
that harbored a plasmid with the phoP-HA genes under the control of a derivative of the lac promoter because a strain with a chromosomal phoQ mutation would constitutively activate the PhoP protein
This was true not only for a strain transcribing the phoP-HA phoQ genes from the wild-type ( i.e. , PhoP-autoregulated ) promoter ( Fig .