As PhoP is a negative regulator of the hilA expression , this decreased expression can not account for the downregulation of the hilA gene by the fliZ mutation .
As PhoP is a negative regulator of the hilA expression , this decreased expression can not account for the downregulation of the hilA gene by the fliZ mutation .
According to the idea that NO represses PhoPQ signaling , transcription of the PhoP-repressed genes ( prg ) fliA ( fig. 5B ) , fliC and hilA was upregulated in response to spermine NONOate treatment ( table S2 ) .
Induction of several PhoP-repressed genes including the SPI-1 transcriptional activator hilA , and fliA and fliC components of the flagellar type III secretion systems [ 47,53,54 ] further support a model in which RNS target PhoPQ signaling .
The response regulator PhoP represses hilA , whereas transcription of pag is activated .
The response regulator PhoP represses hilA , whereas transcription of PhoP-activated genes is activated .