repression of fis transcription To investigate whether RpoS affected the level of transcription of the activity of the fis promoter in the SL1344 rpoS mutant was monitored during the growth of the culture .
repression of fis transcription To investigate whether RpoS affected the level of transcription of fis in the SL1344 rpoS mutant was monitored during the growth of the culture .
Our data indicate that the presence of the RpoS sigma factor correlates with repression of the fis gene .
As it is unlikely that RpoS represses the fis promoter directly , repression may involve an indirect negative effect .
By reducing the number of RpoDcontaining holoenzymes , RpoS may downregulate that of the fis gene .