Like marRAB , acrAB are positively regulated by Rob .
While Rosenberg et al. presented evidence that mar is not necessary for bile-salt-mediated activation of acrAB in E. coli , they observed that induction of acrAB by bile-salts is dependent upon Rob .
Other regulators of Rob did not contrib-ute to acrAB induction by indole in Salmonella .
Also , acrAB is reportedly induced by bile in a Robdependent manner in E. coli .
In E. coli , the transcriptional factor Rob plays a major role in inducing acrAB expression in response to bile .
8 -- 13 _ shown that Rob , play a role in antimicrobial resistance by activating acrAB
In E. coli , the transcriptional factor Rob plays a major role in inducing acrAB expression in response to bile .