Recent work by Lee et al. revealed that the expression of ssrAB itself is regulated by OmpR ± Env .
As OmpR also controls the expression of the acid-induced virulence operon ssrAB , acid shock induction of ompR was examined to gain insight into how Salmonella links virulence with survival at extreme acid-pH .
Consistent with OmpR have recently shown that OmpR regulates the acid induction of the ssrAB two-component signal transduction system located within the Spi2 pathogenicity island .
As OmpR also controls the expression of the acid-induced virulence operon ssrAB , acid shock induction of ompR was examined to gain insight into how Salmonella links virulence with survival at extreme acid-pH .
Consistent with OmpR have recently shown that OmpR regulates the acid induction of the ssrAB two-component signal transduction system located within the Spi2 pathogenicity island .
turn _ regulated by the OmpR -- EnvZ two-component system , by direct binding of OmpR to the ssrAB promoter
turn _ regulated by the OmpR -- EnvZ two-component system , by direct binding of OmpR to the ssrAB promoter
OmpR binds directly to the ssrAB promoter .
These results indicate that other than ssrAB , is not a result of direct binding of OmpR to their promoters .
OmpR is also known to interact with the endogenous two-component regulator of SPI-2 , ssrAB in S. Typhimurium .
OmpR activates SPI-2 genes by binding to the promoter of the ssrAB operon to induce expression of SsrB proteins .
OmpR activates SPI-2 genes by binding to the promoter of the ssrAB operon to induce expression of SsrA proteins .
The expression of the SsrA-SsrB two-component system is regulated by the OmpR-EnvZ two-component system by OmpR binding directly to the ssrAB promoter .
Since OmpR binds to the 83/6 region , it is possible that the sequence is involved in the positive regulation of ssrAB by OmpR .
To determine how OmpR to regulate the expression of ssrAB in response to different growth-conditions is a matter of future studies .
To determine how OmpR to regulate the expression of ssrAB in response to different growth-conditions is a matter of our current .