HilD do not seem to regulate expression of hilD .
These results indicate that Lon is involved in the autoregulation of hilD transcription by modulating amounts of HilD .
This work demonstrates the regulation of hilD by HilD .
Of these regulators , HilD can be considered as the most important single regulator of PhilA since the hilD knockout strain shows nearly basal levels of HilA under inducing conditions .
Transcription of hilD is under the control of an autogenous , positive feedback loop by the HilD product ( Ellermeier et al. 2005 ; Slauc Figure 3 .
Transcription of hilD is under the control of an autogenous , positive feedback loop by the HilD product ( Ellermeier et al. 2005 ; Ellermeier Figure 3 .
Interestingly , hilD mRNA levels have been found to be dependent upon Dam activity , thus suggesting posttranscriptional control of HilD expression .
Interestingly , hilD mRNA levels have been found to be dependent upon DNA adenine methylation activity , thus suggesting posttranscriptional control of HilD expression .
HilD also directly controls the expression of the SPI-1 genes hilD .
The evidence that L-arabinose regulates SPI-1 expression through HilD suggested that hilD expression itself might be controlled by L-arabinose .
CpxR Represses hilD and thus Indirectly Affects HilD-regulated Genes Several global regulators control the expression of the SPI-1 genes by directly affecting the expression , activity or concentration of FLAG-tagged gene , was analyzed by Western blotting using monoclonal anti-FLAG or polyclonal anti-SseB antibodies .
The C-terminal domain of RNAPa has been shown to be important for transcription of HilD-regulated genes in-vivo , as the mutation of leucine 289 to phenylalanine within this domain fails to induced hilA expression , similarly to a hilD null mutant ( Boddicker et al. , 2003 ) .
The control of HilD by Pat was through post-transcriptional mechanisms , moderately repressing hilD translation while significantly reducing HilD stability .
Thus , although HilD is capable of auto-regulation , the results could not be due to the loss of this regulatory protein controlling its own expres ¬ Pat post-transcriptionally regulates HilD The regulation of hilD is complex ; hilD is also regulated by the transcriptional regulators HilC and RtsA , which constitute a feed-forward circuit to control the downstream SPI1 regulator Hil .
Thus , although HilD is capable of auto-regulation , the results could not be due to the loss of this regulatory protein controlling its own expres ¬ Pat post-transcriptionally regulates HilD The regulation of hilD is complex ; hilD regulates itsel .
Because the extent of the regulatory effect was only 1.5 fold , we tested whether the IscR‐mediated regulation of hilD had any effect on the expression of downstream HilD‐regulated genes .
Indeed , we showed that apo‐IscR , which prevails in an iscU mutant , down‐regulates the expression of the master regulator hilD and thereby of several downstream HilD‐regulated genes .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the grant D0480901 , UR Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
activity of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , grant 2014SGR1260 , CB , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by grants BIO2010-15417 and AGL2013-45339-R , CB , the Catalonian government , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , grant 2014SGR1260 , CB , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , grant 2012/ACUP/00048 , CB , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the Engineering Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , d Ce Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
Expression of HilD are tightly Funding : This work was supported by Competitiveness , the Catalonian government , the RecerCaixa program , the Swedish Research Council Natural Sciences Abstract Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar 1 Departament de Genètica , Microbiologia i Estadıstica , Universitat de Barcelona , Barcelona , Spain , 2 Department of Microbiology , , Tum Biology , Karolinska Institutet , Stockholm , Sweden The invasion of epithelial cells by Salmonella enterica serovar Typhimurium is a very tightly regulated proce .
https://doi.org/10.1371/journal.ppat.1006312.g004 The 3 
https://doi.org/10.1371/journal.ppat.1006312.g004 The 3 
https://doi.org/10.1371/journal.ppat.1006312.g004 The 3 
HilD is the dominant regulator of the system , as a hilD mutant had almost no hilA expression , whereas deletion of either rtsA decreased hilA expression less significantly .
HilD is the dominant regulator of the system , as a hilD mutant had almost no hilA expression , whereas deletion of either hilC decreased hilA expression less significantly .
Although the actual mechanism is known in only a few cases , we have shown that regulation is primarily through either translation of the hilD message or control of HilD protein activity .