Looking at the 50UTR region of avrA , it is very likely that the CsrA action takes place at the upstream untranslated region of the mRNA itself , maybe by binding to the GGA motif on 25 NT of 50UTR region proximal to the first ATG of the avrA open reading frame , or by opening ATG for translation , depending on the above-mentioned critical concentration .
Looking at the 50UTR region of avrA , it is very likely that the CsrA action takes place at the upstream untranslated region of the mRNA itself , maybe by binding to the GGA motif on 25 NT of 50UTR region proximal to the first ATG of the avrA open reading frame , or by opening the RBS , depending on the above-mentioned critical concentration .
Looking at the 50UTR region of avrA , it is very likely that the CsrA action takes place at the upstream untranslated region of the mRNA itself , maybe by binding to the GGA motif on 25 NT of 50UTR region proximal to the first ATG of the avrA open reading frame , or by blocking ATG for translation , depending on the above-mentioned critical concentration .
Looking at the 50UTR region of avrA , it is very likely that the CsrA action takes place at the upstream untranslated region of the mRNA itself , maybe by binding to the GGA motif on 25 NT of 50UTR region proximal to the first ATG of the avrA open reading frame , or by blocking the RBS , depending on the above-mentioned critical concentration .
it is suggested here that the CsrA protein can directly regulate the avrA mRNA
It can be suggested therefore that any post-transcrip-tional regulation by the cooperative action of CsrA destabilising the avrA mRNA provides a extremely sensitive means to alter virulence gene expression in response to environmental conditions .
It can be suggested therefore that any post-transcrip-tional regulation by the cooperative action of CsrA destabilising the avrA mRNA provides a rapid means to alter virulence gene expression in response to environmental conditions .
It can be suggested therefore that any post-transcrip-tional regulation by the cooperative action of CsrA stabilising the avrA mRNA provides a extremely sensitive means to alter virulence gene expression in response to environmental conditions .
It can be suggested therefore that any post-transcrip-tional regulation by the cooperative action of CsrA stabilising the avrA mRNA provides a rapid means to alter virulence gene expression in response to environmental conditions .