Schneiders T. , Levy S.B. MarA-mediated transcriptional repression of the rob promoter .
In agreement with these results , the molecular mechanism of repression of rob by MarA was shown to be due to steric hindrance at the level of the promoter region .
Furthermore , we demonstrate that MarA mediate repression of rob by binding to its promoter region .
rob is negatively regulated by MarA The transcript levels of rob in the DsoxS strains were repressed after treatment with NaOCl as in the wild type .
rob is negatively regulated by MarA The transcript levels of rob in the DmarA strains were repressed after treatment with NaOCl as in the wild type .
This confirms our previous results that repression of rob in the must have been due to overexpression of MarA .
The results above suggest that MarA could mediate together a repression of rob in response to NaOCl .
mean ± SD NaOC _ supporting our hypothesis of a repression of rob by both MarA and Sox
other studies _ performed in E. coli where rob was shown to be negatively regulated by both MarA by a direct interaction with its promoter region
the expression of rob is repressed by the transcription factors MarA
J Biol Chem 277:30463 -- 30468 Schneiders T , Levy SB MarA-mediated transcriptional repression of the rob promoter .