This lack of an in-vitro phenotype agrees with the fact that RpoS positively regulates spvR expression .
Indeed , RpoS participates in the induction of spvR .
It is possible that the downregulation of sefA in TSP-adapted cells may result from the upregulation of RpoS because RpoS is a positive regulator of spvR expression .
It is possible that the upregulation of spvR may result from the upregulation of RpoS because RpoS is a negative regulator of sefA expression .
It is possible that the upregulation of spvR may result from the upregulation of RpoS because RpoS is a positive regulator of spvR expression .
It is possible that the upregulation of spvR may result from the upregulation of RpoS because RpoS is a positive regulator of spvR expression .