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Fnr has been previously reported to be a negative regulator of hilA in S. Typhimurium , as loss of Fnr caused a 1.5-to 2-fold increase of hilA expression under in-vitro SPI-1-inducing conditions .
Fnr has been previously reported to be a negative regulator of hilA in S. Typhimurium , as loss of Fnr caused a 1.5-to 2-fold increase of hilA expression under in-vitro high salt .
Fnr has been previously reported to be a negative regulator of hilA in S. Typhimurium , as loss of Fnr caused a 1.5-to 2-fold increase of hilA expression under in-vitro low O2 .
However , whether the repression of hilA by Fnr was induced by low O2 was not clarified in those studies .