Interestingly , slyA of S. Typhi-murium has been shown to be induced via the PhoP/PhoQ two-component system following internalization of the bacteria by macrophages .
the PhoP/PhoQ 2-com-ponent system activates slyA transcription by sensing Mg2
Transcription of the slyA locus is activated by the PhoP/PhoQ 2-component system .