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Delete abstracts-titles-annotated.txt

1 -25505594|t|Assessment of the effect of potential antifibrotic compounds on total and aVb6 integrin-mediated TGF-b <v>activation.</v>
2 -28493530|t|M2 macrophages <v>induce </v><g>EMT</g> through the <g>TGF-b</g>/<g>Smad2</g> signaling pathway
3 -21269063|t|Resveratrol inhibits transforming growth factor-b-induced proliferation and differentiation of ex vivo human lung fibroblasts into myofibroblasts through <g>ERK</g>/<g>Akt</g> <u>inhibition </u>and <g>PTEN</g> restoration
4 -23962103|t|Up-regulation of heparan sulfate 6-O-sulfation in <d>idiopathic pulmonary fibrosis</d>
5 -25845491|t|Immunoglobulin A in serum: an old acquaintance as a new prognostic biomarker in <d>idiopathic pulmonary fibrosis</d>
6 -16607487|t|[Pulmonary fibrosis--a therapeutic dilemma?]
7 -23924348|t|<g>Syndecan-2</g> exerts antifibrotic effects by promoting <g>caveolin-1</g>-mediated transforming growth factor-b receptor I internalization and inhibiting transforming growth factor-b1 signaling
8 -14653626|t|Modulation of specific beta cell gene (re)expression during in vitro expansion of human pancreatic islet cells
9 -10188109|t|<r>Regulation </r>of human lung fibroblast <g>C1q</g>-receptors by <g>transforming growth factor-beta</g> and <g>tumor necrosis factor-alpha</g>
10 -27494713|t|Amplification of <g>TGFb</g>
11 -18402687|t|Comparison between conventional and "clinical" assessment of experimental lung <d>fibrosis</d>
12 -12610869|t|[<d>Idiopathic pulmonary fibrosis</d> and <d>lung cancer</d>]
13 -23043074|t|<g>Periostin</g> promotes <d>fibrosis</d> and predicts progression in patients with <d>idiopathic pulmonary fibrosis</d>
14 -24276150|t|<g>CCN5</g> <v>overexpression </v>inhibits profibrotic phenotypes via the <g>PI3K</g>/Akt signaling pathway in lung fibroblasts isolated from patients with <d>idiopathic pulmonary fibrosis</d> and in an in vivo model of <d>lung fibrosis</d>
15 -28420366|t|Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by <r>regulating </r><g>Nrf2</g>/<g>Bach1</g> equilibrium
16 -16842247|t|<g>Extracellular superoxide dismutase</g> has a highly specific <l>localization </l>in <d>idiopathic pulmonary fibrosis</d>/<d>usual interstitial pneumonia</d>
17 -20676040|t|Signaling pathways in the epithelial origins of <d>pulmonary fibrosis</d>
18 -18344408|t|Overexpression of <d>squamous cell carcinoma</d> antigen in <d>idiopathic pulmonary fibrosis</d>: clinicopathological correlations
19 -28847533|t|High levels of <g>IL-6</g> and <g>IL-8</g> characterize early-on <d>idiopathic pulmonary fibrosis</d> acute exacerbations
20 -28314802|t|An ex vivo model to induce early <d>fibrosis</d>-like changes in human precision-cut lung slices
21 -11713352|t|Regulation of the effects of <g>TGF-beta 1</g> by activation of latent <g>TGF-beta 1</g> and differential <e>expression </e>of <g>TGF-beta receptors (T beta R-I and T beta R-II</g>) in <d>idiopathic pulmonary fibrosis</d>
22 -28986385|t|The role of halofuginone in fibrosis: more to be explored? Fibrosis, which can be defined as an abnormal or excessive accumulation of extracellular matrix (ECM), particularly fibrillar collagens, is a key driver of progressive organ dysfunction in many inflammatory and metabolic diseases, including idiopathic pulmonary fibrosis (IPF), cirrhosis, nephropathy, and oral submucous fibrosis (OSF)
23 -20081107|t|Genomewide RNA expression profiling in lung identifies distinct signatures in <d>idiopathic pulmonary arterial hypertension</d> and <d>secondary pulmonary hypertension</d>
24 -27070485|t|Establishment of the mouse model of acute exacerbation of <d>idiopathic pulmonary fibrosis</d>
25 -23143540|t|Dehydroepiandrosterone has strong antifibrotic effects and is decreased in <d>idiopathic pulmonary fibrosis</d>
26 -24418172|t|Peripheral depletion of NK cells and imbalance of the Treg/Th17 axis in <d>idiopathic pulmonary fibrosis</d> patients
27 -27869174|t|Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with <d>Idiopathic Pulmonary Fibrosis</d>
28 -27576730|t|Metformin <d>attenuates lung fibrosis</d> development via <g>NOX4</g> <u>suppression.</u>
29 -25451236|t|<g>Plasminogen activator inhibitor 1</g>, fibroblast apoptosis resistance, and aging-related susceptibility to lung <d>fibrosis</d>
30 -23288928|t|<u>Inhibition </u>of <g>HSP27</g> blocks <d>fibrosis</d> development and EMT features by promoting <g>Snail</g> degradation
31 -23815594|t|Cytokine gene polymorphisms and serum cytokine levels in patients with <d>idiopathic pulmonary fibrosis</d>
32 -26315535|t|<g>miR-9-5p</g> suppresses pro-fibrogenic transformation of fibroblasts and prevents organ <d>fibrosis</d> by targeting <g>NOX4</g> and <g>TGFBR2</g>
33 -27215343|t|Raised serum levels of <g>IGFBP-1</g> and <g>IGFBP-2</g> in <d>idiopathic pulmonary fibrosis</d>
34 -28414923|t|Determining the True Selectivity Profile of av Integrin Ligands Using Radioligand Binding: Applying an Old Solution to a New Problem
35 -21513813|t|Signalling pathways from NADPH oxidase-4 to <d>idiopathic pulmonary fibrosis</d>
36 -19460787|t|<r>Effects </r>of a leukotriene B4 receptor antagonist on bleomycin-induced <d>pulmonary fibrosis</d>
37 -25680454|t|Tumor <d>necrosis</d> factor superfamily 14 (<d>LIGHT</d>) controls <g>thymic stromal lymphopoietin</g> to drive <d>pulmonary fibrosis</d>
38 -15117744|t|<g>Pigment epithelium-derived factor</g> in <d>idiopathic pulmonary fibrosis</d>: a role in aberrant angiogenesis
39 -27071460|t|Profibrotic role of <g>WNT10A</g> via <g>TGF-b</g> signaling in <d>idiopathic pulmonary fibrosis</d>
40 -29351444|t|Activated human T lymphocytes inhibit <g>TGFb</g>-induced fibroblast to myofibroblast differentiation via prostaglandins D2 and E2
41 -17710235|t|The Role of PPARs in Lung <d>Fibrosis</d>
42 -26442443|t|Methylation-mediated <g>BMPER</g> <e>expression </e>in fibroblast activation in vitro and lung <d>fibrosis</d> in mice in vivo
43 -23499992|t|<d>Fibrosis</d> of two: Epithelial cell-fibroblast interactions in <d>pulmonary fibrosis</d>
44 -23470623|t|Peptide-mediated inhibition of <g>mitogen-activated protein kinase-activated protein kinase-2</g> ameliorates bleomycin-induced <d>pulmonary fibrosis</d>
45 -22240154|t|Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a <g>TGF-b1</g>-dependent mechanism
46 -29206498|t|The potential application of strategic released apigenin from polymeric carrier in pulmonary fibrosis
47 -19614606|t|Role of integrin-<v>mediated </v><g>TGFbeta</g> <v>activation </v>in the pathogenesis of <d>pulmonary fibrosis</d>
48 -12540741|t|Novel pharmacological approaches to manage <d>interstitial lung fibrosis</d> in the twenty-first century
49 -26276873|t|Lipoxin A4 Attenuates Constitutive and <g>TGF-b1</g>-Dependent Profibrotic Activity in Human Lung Myofibroblasts
50 -23418199|t|<v>Overexpression </v>of <g>Sulf2</g> in <d>idiopathic pulmonary fibrosis</d>
51 -25906080|t|Essential role for the <g>ATG4B</g> protease and autophagy in bleomycin-induced <d>pulmonary fibrosis</d>
52 -23915349|t|Microarray profiling reveals <u>suppressed </u>interferon stimulated gene program in fibroblasts from scleroderma-associated <d>interstitial lung disease</d>
53 -16816361|t|<g>Bone morphogenetic protein-4</g> inhibitor <g>gremlin</g> is <v>overexpressed </v>in <d>idiopathic pulmonary fibrosis</d>
54 -28239659|t|<g>Hsp90</g> <r>regulation </r>of fibroblast activation in <d>pulmonary fibrosis</d>
55 -25111852|t|<g>Glucagon like peptide-1</g> attenuates bleomycin-induced <d>pulmonary fibrosis</d>, involving the <u>inactivation </u>of NF-kB in mice
56 -17163490|t|Smooth muscle alpha-actin <e>expression </e>and myofibroblast differentiation by <g>TGFbeta</g> are <v>dependent </v>upon <g>MK2</g>
57 -24392001|t|The K+ channel <g>KCa3.1</g> as a novel target for <d>idiopathic pulmonary fibrosis</d>
58 -27769060|t|<g>MiR-185</g>/<g>AKT</g> and <g>miR-29a</g>/collagen 1a pathways are <v>activated </v>in <d>IPF</d>
59 -24762191|t|Arsenic trioxide inhibits transforming growth factor-b1-induced <d>fibroblast to myofibroblast differentiation</d> in vitro and bleomycin induced lung <d>fibrosis</d> in vivo
60 -22246864|t|<g>Spiruchostatin A</g> inhibits proliferation and differentiation of fibroblasts from patients with <d>pulmonary fibrosis</d>
61 -26610737|t|<v>Elevated </v><g>sL1</g>-CAM levels in BALF and serum of <d>IPF</d> patients
62 -23755232|t|Lung myofibroblasts are characterized by <u>down-regulated </u><g>cyclooxygenase-2</g> and its main metabolite, prostaglandin E2
63 -26934369|t|Cigarette Smoke Enhances the Expression of Profibrotic Molecules in Alveolar Epithelial Cells
64 -24265486|t|<g>Wilms' tumor 1</g> (<g>Wt1</g>) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in <d>idiopathic pulmonary fibrosis</d>
65 -26787543|t|<g>miR-26a</g> suppresses EMT by disrupting the <g>Lin28B</g>/<g>let-7d</g> axis: potential cross-talks among miRNAs in <d>IPF</d>
66 -26542979|t|microRNA-1343 attenuates pathways of <d>fibrosis</d> by targeting the <g>TGF-b</g> receptors
67 -23760654|t|Kinase <u>inhibitors </u>fail to induce mesenchymal-epithelial transition in fibroblasts from fibrotic lung tissue
68 -16948840|t|Microarray identifies ADAM family members as key responders to <g>TGF-beta1</g> in alveolar epithelial cells
69 -18245174|t|<g>Transgelin</g> is a direct target of <g>TGF-beta</g>/<g>Smad3</g>-dependent epithelial cell <d>migration in lung fibrosis</d>
70 -25929803|t|The mannose-6-phosphate analogue, PXS64, inhibits <d>fibrosis</d> via <g>TGF-b1</g> pathway in human lung fibroblasts
71 -29113323|t|<u>Reduced </u><e>expression </e>of <g>BMP3</g> contributes to the development of <d>pulmonary fibrosis</d> and predicts the unfavorable prognosis in IIP patients
72 -27080864|t|Role of <g>CD248</g> as a potential severity marker in <d>idiopathic pulmonary fibrosis</d>
73 -23911740|t|<g>IL-4</g> polymorphisms, HRCT score and lung tissue markers in <d>idiopathic pulmonary fibrosis</d>
74 -21511034|t|Early growth response transcription factors: key mediators of <d>fibrosis</d> and novel targets for anti-fibrotic therapy
75 -27815256|t|<g>Toll-like receptor 4</g> activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with <d>IPF</d>
76 -12485463|t|Titration of non-replicating adenovirus as a vector for <v>transducing </v>active <g>TGF-beta1</g> gene <e>expression </e>causing <d>inflammation</d> and fibrogenesis in the lungs of C57BL/6 mice
77 -23468849|t|Herpes <d>virus infection</d> is associated with vascular remodeling and <d>pulmonary hypertension</d> in <d>idiopathic pulmonary fibrosis</d>
78 -22446029|t|Effect of substrate stiffness on pulmonary fibroblast activation by <g>TGF-b</g>
79 -24625972|t|<g>BAX inhibitor-1</g>-associated <g>V-ATPase</g> glycosylation <v>enhances </v>collagen degradation in <d>pulmonary fibrosis</d>
80 -26286721|t|Sphingosine-1-phosphate lyase is an endogenous suppressor of <d>pulmonary fibrosis</d>: role of <g>S1P</g> signalling and autophagy
81 -22703534|t|<g>Nuclear factor erythroid 2-related factor 2</g> nuclear translocation induces <d>myofibroblastic dedifferentiation</d> in <d>idiopathic pulmonary fibrosis</d>
82 -25575513|t|<g>Matrix metalloproteinase (MMP)-19</g> <u>deficient </u>fibroblasts display a profibrotic phenotype
83 -25214520|t|A translational preclinical model of <d>interstitial pulmonary fibrosis</d> and <d>pulmonary hypertension</d>: mechanistic pathways driving disease pathophysiology
84 -24529509|t|Comparative study of transforming growth factor-b signalling and regulatory molecules in human and canine <d>idiopathic pulmonary fibrosis</d>
85 -25162417|t|A critical role for the <g>mTORC2</g> pathway in <d>lung fibrosis</d>
86 -19117745|t|Cytokine gene polymorphisms and BALF cytokine levels in <d>interstitial lung diseases</d>
87 -23439433|t|<g>PI3K</g> p110y <v>overexpression </v>in <d>idiopathic pulmonary fibrosis lung</d> tissue and fibroblast cells: in vitro effects of its inhibition
88 -23967091|t|Low-dose paclitaxel ameliorates <d>pulmonary fibrosis</d> by suppressing <g>TGF-b1</g>/<g>Smad3</g> pathway via <g>miR-140</g> upregulation
89 -21420029|t|MicroRNAs in <d>idiopathic pulmonary fibrosis</d>
90 -27867035|t|Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung <d>Fibrosis</d>
91 -16933466|t|Membrane type-matrix metalloproteinases in <d>idiopathic pulmonary fibrosis</d>
92 -26415510|t|<g>BARD1</g> mediates <g>TGF-b</g> signaling in <d>pulmonary fibrosis</d>
93 -26160872|t|Increased <d>alveolar</d> soluble <g>annexin V</g> promotes <d>lung inflammation</d> and <d>fibrosis</d>
94 -22815997|t|Autophagy in <d>idiopathic pulmonary fibrosis</d>
95 -28213468|t|Microencapsulation of lefty-secreting engineered cells for <d>pulmonary fibrosis</d> therapy in mice
96 -27185272|t|Bile acids induce activation of alveolar epithelial cells and lung fibroblasts through farnesoid X receptor-dependent and independent pathways
97 -21044893|t|<g>TGF-beta</g> driven lung <d>fibrosis</d> is macrophage dependent and blocked by Serum amyloid P
98 -28495857|t|<g>TGF-b1</g> <v>induces </v><g>Fstl1</g> via the <g>Smad3</g>-<g>c-Jun</g> pathway in lung fibroblasts
99 -26895395|t|Exercise <u>Reduces </u>Lung <d>Fibrosis</d>
100 -28254114|t|Genetic polymorphism in <g>matrix metalloproteinase-9</g> and <g>transforming growth factor-b1</g> and susceptibility to <d>combined pulmonary fibrosis</d> and <d>emphysema</d> in a Chinese population
101 -19543300|t|MS80, a novel sulfated oligosaccharide, inhibits <d>pulmonary fibrosis</d> by targeting <g>TGF-beta1</g> both in vitro and in vivo
102 -27002405|t|Protective role of gambogic acid in experimental <d>pulmonary fibrosis</d> in vitro and in vivo
103 -28178340|t|Sputum biomarkers in <d>IPF</d>: Evidence for raised gene <e>expression </e>and protein level of <g>IGFBP-2</g>, <g>IL-8</g> and <g>MMP-7</g>
104 -23764846|t|Sorafenib ameliorates bleomycin-induced <d>pulmonary fibrosis</d>: potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation
105 -25260753|t|<g>Forkhead Box F1</g> (<g>FOXF1</g>) <u>represses </u>cell growth, COL1 and <g>ARPC2</g> <e>expression </e>in lung fibroblasts in vitro
106 -12899768|t|[Different cytokine profiles in <d>usual interstitial pneumonia</d> and <d>nonspecific interstitial pneumonia</d>]
107 -27350126|t|Targeting of <g>Discoidin Domain Receptor 2</g> (<g>DDR2</g>) Prevents Myofibroblast Activation and Neovessel Formation During <d>Pulmonary Fibrosis</d>
108 -27765762|t|<g>MicroRNA-29c</g> regulates apoptosis sensitivity via modulation of the cell-surface death receptor, Fas, in lung fibroblasts
109 -23817018|t|Simvastatin attenuates <g>TGF-b1</g>-induced epithelial-mesenchymal transition in human alveolar epithelial cells
110 -24890164|t|Expression of <g>suppressor of cytokine signaling 1</g> in the peripheral blood of patients with <d>idiopathic pulmonary fibrosis</d>
111 -19966781|t|<g>Prostaglandin F(2alpha) receptor</g> signaling facilitates bleomycin-induced <d>pulmonary fibrosis</d> independently of transforming growth factor-beta
112 -23043088|t|Profibrotic role of <g>miR-154</g> in <d>pulmonary fibrosis</d>
113 -21471103|t|Role of <g>protease-activated receptor-2</g> in <d>idiopathic pulmonary fibrosis</d>
114 -10337028|t|<e>Expression </e>of mucosa-related integrin alphaEbeta7 on <d>alveolar T</d> cells in <d>interstitial lung diseases</d>
115 -8163656|t|Anchorage-independent colony growth of pulmonary fibroblasts derived from fibrotic human lung tissue
116 -8520791|t|Cytoskeletal protein modulation in <d>pulmonary alveolar myofibroblasts</d> during <d>idiopathic pulmonary fibrosis</d>
117 -24344132|t|<g>Aortic carboxypeptidase-like protein</g> (<g>ACLP</g>) enhances lung myofibroblast differentiation through transforming growth factor b receptor-dependent and -independent pathways
118 -18569384|t|The latent form of <g>TGFbeta(1)</g> is induced by <g>TNFalpha</g> through an <g>ERK</g> specific pathway and is <v>activated </v>by asbestos-derived reactive oxygen species in vitro and in vivo
119 -21700912|t|<g>Transglutaminase 2</g> and its role in <d>pulmonary fibrosis</d>
120 -20715983|t|Differential effects of human neutrophil peptide-1 on growth factor and <g>interleukin-8</g> production by human lung fibroblasts and epithelial cells
121 -27439438|t|Sunitinib, a Small-Molecule Kinase <u>Inhibitor,</u>
122 -11350829|t|Fibroblasts from <d>idiopathic pulmonary fibrosis</d> and normal lungs differ in growth rate, apoptosis, and tissue <u>inhibitor </u>of metalloproteinases <e>expression.</e> <d>Idiopathic pulmonary fibrosis</d> (<d>IPF</d>) is a <d>chronic lung disorder</d> characterized by fibroblast proliferation and extracellular matrix accumulation
123 -24515257|t|Transforming growth factor-b1 downregulates <g>vascular endothelial growth factor</g>-D expression in human lung fibroblasts via the <g>Jun NH2-terminal kinase</g> signaling pathway
124 -27604640|t|<g>Ubiquitin carboxyl-terminal hydrolase-L5</g> promotes <g>TGFb-1</g> signaling by de-ubiquitinating and stabilizing <g>Smad2</g>/<g>Smad3</g> in <d>pulmonary fibrosis</d>
125 -26883801|t|<g>Chop</g>
126 -28360109|t|<g>Focal adhesion kinase</g> signaling determines the fate of lung epithelial cells in response to <g>TGF-b</g>
127 -29031221|t|Effects of particulate matter from straw burning on <d>lung fibrosis</d> in mice
128 -27513632|t|<g>miR -221</g> targets <g>HMGA2</g> to inhibit bleomycin -induced <d>pulmonary fibrosis</d> by regulating <g>TGF -b1</g>/<g>Smad3</g>-induced EMT
129 -26386411|t|<g>VCAM-1</g> is a <g>TGF-b1</g> inducible gene <v>upregulated </v>in <d>idiopathic pulmonary fibrosis</d>
130 -27582065|t|<g>EZH2</g> enhances the differentiation of fibroblasts into myofibroblasts in <d>idiopathic pulmonary fibrosis</d>
131 -20388759|t|<u>Suppression </u>of <g>plasminogen activator inhibitor-1</g> by RNA interference attenuates <d>pulmonary fibrosis</d>
132 -24613900|t|Effect of pirfenidone on proliferation, <g>TGF-b</g>-induced myofibroblast differentiation and fibrogenic activity of primary human lung fibroblasts
133 -26867691|t|<g>WISP1</g> mediates <g>IL-6</g>-dependent proliferation in primary human lung fibroblasts
134 -22295148|t|<d>Idiopathic pulmonary fibrosis</d>: immunohistochemical analysis provides fresh insights into lung tissue remodelling with implications for novel prognostic markers
135 -28182573|t|Amplified canonical transforming growth factor-b signalling<i>via</i><d>heat shock</d> protein 90 in <d>pulmonary fibrosis</d>
136 -16948989|t|[Quantifying plasma levels of <g>transforming growth factor beta1</g> in <d>idiopathic pulmonary fibrosis</d>]
137 -26884454|t|The matricellular protein <g>CCN1</g> enhances <g>TGF-b1</g>/<g>SMAD3</g>-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to <d>lung injury</d>
138 -29045477|t|Tubastatin ameliorates <d>pulmonary fibrosis</d> by targeting the TGFb-PI3K-<g>Akt</g> pathway
139 -25555634|t|<v>Upregulation </v>of alveolar <e>levels </e>of activin B, but not activin A, in lungs of west highland white terriers with <d>idiopathic pulmonary fibrosis</d> and <d>diffuse alveolar damage</d>
140 -21577212|t|Absence of <g>Thy-1</g> results in <g>TGF-b</g> induced <g>MMP-9</g> expression and confers a profibrotic phenotype to human lung fibroblasts
141 -25064447|t|Lung fibrotic <g>tenascin-C</g> <v>upregulation </v>is associated with other extracellular matrix proteins and <v>induced </v>by TGFb1
142 -28771711|t|Tannic acid attenuates TGF-b1-induced epithelial-to-mesenchymal transition by effectively intervening TGF-b signaling in lung epithelial cells
143 -28922731|t|Shikonin suppresses pulmonary fibroblasts proliferation and activation by <r>regulating </r><g>Akt</g> and <g>p38</g>
144 -19700647|t|Abrogation of <g>TGF-beta1</g>-induced fibroblast-myofibroblast differentiation by <g>histone deacetylase</g> <u>inhibition.</u> <d>Idiopathic pulmonary fibrosis</d> (<d>IPF</d>) is a devastating disease with no known effective pharmacological therapy
145 -29440315|t|<g>JAK2</g> mediates <d>lung fibrosis</d>, <d>pulmonary vascular remodelling</d> and <d>hypertension</d> in <d>idiopathic pulmonary fibrosis</d>: an experimental study
146 -28455433|t|<g>AKT2</g>
147 -25524739|t|Regulation of myofibroblast differentiation by <g>miR-424</g> during epithelial-to-mesenchymal transition
148 -25959210|t|Bleomycin in the setting of <d>lung fibrosis</d> induction: From biological mechanisms to counteractions
149 -28726637|t|MicroRNA-101 attenuates pulmonary fibrosis by inhibiting fibroblast proliferation and activation
150 -26887531|t|<g>Extracellular Matrix Metalloproteinase Inducer</g> (<g>EMMPRIN</g>) promotes lung fibroblast proliferation, survival and differentiation to myofibroblasts
151 -25365224|t|<g>TRPV4</g> mediates myofibroblast differentiation and <d>pulmonary fibrosis</d> in mice
152 -28557137|t|Modulation of <g>CD11c</g>+ lung dendritic cells in respect to <g>TGF-b</g> in experimental <d>pulmonary fibrosis</d>
153 -27878256|t|Melatonin attenuates <g>TGFb1</g>-induced epithelial-mesenchymal transition in lung alveolar epithelial cells
154 -23442250|t|Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced <d>pulmonary fibrosis progression</d>
155 -26600305|t|Fibrogenic Lung Injury Induces Non-Cell-Autonomous Fibroblast Invasion
156 -22802287|t|<g>TGF-b</g> activation and lung <d>fibrosis</d>
157 -15855634|t|Induction of epithelial-mesenchymal transition in alveolar epithelial cells by <g>transforming growth factor-beta1</g>: potential role in <d>idiopathic pulmonary fibrosis</d>
158 -26059457|t|<r>Deregulation </r>of selective autophagy during aging and <d>pulmonary fibrosis</d>: the role of <g>TGFb1</g>
159 -7767546|t|<v>Increased </v>interleukin-1 receptor antagonist in <d>idiopathic pulmonary fibrosis</d>
160 -19355895|t|Recent advances in molecular targets and treatment of <d>idiopathic pulmonary fibrosis</d>: focus on <g>TGFbeta</g> signaling and the myofibroblast
161 -29067109|t|<g>TIAM1</g> inhibits lung fibroblast differentiation in <d>pulmonary fibrosis</d>
162 -23315259|t|Targeting <g>sphingosine kinase 1</g> attenuates bleomycin-induced <d>pulmonary fibrosis</d>
163 -12570673|t|Re-evaluation of fibrogenic cytokines in <d>lung fibrosis</d>
164 -16738206|t|Targeting genes for treatment in <d>idiopathic pulmonary fibrosis</d>: challenges and opportunities, promises and pitfalls
165 -16574935|t|Defect of pro-<g>hepatocyte growth factor</g> activation by fibroblasts in <d>idiopathic pulmonary fibrosis</d>
166 -25785991|t|Epithelial Cell Mitochondrial Dysfunction and <g>PINK1</g>
167 -23258233|t|<g>Bone morphogenetic protein</g>-inducer tilorone identified by high-throughput screening is antifibrotic in vivo
168 -23399488|t|Pleural mesothelial cell differentiation and invasion in <d>fibrogenic lung injury</d>
169 -12598227|t|<l>Release </l>of biologically active <g>TGF-beta1</g> by alveolar epithelial cells results in <d>pulmonary fibrosis</d>
170 -28821630|t|<g>IL-17A</g> deficiency mitigates bleomycin-induced complement activation during <d>lung fibrosis</d>
171 -28860144|t|IPF lung fibroblasts have a senescent phenotype
172 -16776827|t|<g>RhoA</g> signaling <r>modulates </r><g>cyclin D1</g> <e>expression </e>in human lung fibroblasts; implications for <d>idiopathic pulmonary fibrosis</d>
173 -25697336|t|Studies of <g>hepatocyte growth factor</g> in bronchoalveolar lavage fluid in chronic <d>interstitial lung diseases</d>
174 -29130366|t|Autophagy and <d>inflammation</d> in chronic <d>respiratory disease</d>
175 -21743278|t|Inhibitory effect of <g>receptor for advanced glycation end products</g> (<g>RAGE</g>) on the <g>TGF-b</g>-induced alveolar epithelial to mesenchymal transition
176 -15030461|t|Cytokine gene polymorphisms in <d>idiopathic pulmonary fibrosis</d>
177 -22284809|t|The profibrotic cytokine <g>transforming growth factor-b1</g> increases endothelial progenitor cell angiogenic properties
178 -29351434|t|<g>Cub domain containing protein 1</g> (<g>CDCP1</g>) negatively regulates TGFb signaling and myofibroblast differentiation
179 -22095546|t|Regulation of transforming growth factor-b1-driven lung <d>fibrosis</d> by <g>galectin-3</g>
180 -26846484|t|<e>Effects </e>of the <d>tumor</d> suppressor <g>PTEN</g> on the pathogenesis of <d>idiopathic pulmonary fibrosis</d> in Chinese patients
181 -27993290|t|Increased levels of prostaglandin E-major urinary metabolite (PGE-MUM) in chronic fibrosing <d>interstitial pneumonia</d>
182 -27560128|t|Epigenetic <r>Regulation </r>of <g>Caveolin-1</g>
183 -7921435|t|Mechanisms of <d>fibrosis</d> in <d>coal workers' pneumoconiosis</d>
184 -22892132|t|Expression of <g>150-kDa oxygen-regulated protein</g> (<g>ORP150</g>) stimulates bleomycin-induced <d>pulmonary fibrosis and dysfunction</d> in mice
185 -16211459|t|Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts
186 -22227563|t|Role of endoplasmic reticulum stress in age-related susceptibility to lung <d>fibrosis</d>
187 -24478701|t|Are mast cells instrumental for <d>fibrotic diseases</d>? <d>Idiopathic pulmonary fibrosis</d> (<d>IPF</d>) is a <d>fatal lung disorder</d> of unknown etiology characterized by accumulation of lung fibroblasts and extracellular matrix deposition, ultimately leading to compromised tissue architecture and lung function capacity
188 -18621908|t|Alveolar epithelial cell injury with Epstein-Barr virus <v>upregulates </v><g>TGFbeta1</g> <e>expression.</e> <d>Idiopathic pulmonary fibrosis</d> (<d>IPF</d>) is a refractory and lethal <d>interstitial lung disease</d> characterized by alveolar epithelial cells apoptosis, fibroblast proliferation, and ECM protein deposition
189 -19129758|t|<d>Pulmonary fibrosis</d>: pathogenesis, etiology and regulation
190 -22014187|t|Activated MCTC mast cells infiltrate diseased lung areas in <d>cystic fibrosis</d> and <d>idiopathic pulmonary fibrosis</d>
191 -27942594|t|<g>miR</g>-323a-3p regulates <d>lung fibrosis</d> by targeting multiple profibrotic pathways
192 -21253589|t|<g>PPAR</g>-y ligands repress <g>TGFb</g>-induced myofibroblast differentiation by targeting the <g>PI3K</g>/<g>Akt</g> pathway: implications for therapy of <d>fibrosis</d>
193 -28336812|t|<g>TGF-b1</g> <v>stimulates </v><g>HDAC4</g> nucleus-to-cytoplasm <l>translocation </l>and <g>NADPH oxidase 4</g>-derived reactive oxygen species in normal human lung fibroblasts
194 -19924381|t|Effects of <d>cigarette smoke extract</d> on A549 cells and human lung fibroblasts treated with <g>transforming growth factor-beta1</g> in a coculture system
195 -27853171|t|De-ubiquitinating enzyme, <g>USP11</g>, promotes <g>transforming growth factor b-1</g> signaling through stabilization of transforming growth factor b receptor II
196 -27942595|t|Single-cell RNA sequencing identifies diverse roles of epithelial cells in <d>idiopathic pulmonary fibrosis</d>
197 -24594795|t|The antifibrotic effects and mechanisms of microRNA-26a action in <d>idiopathic pulmonary fibrosis</d>
198 -26264443|t|Phosphatase and tensin homolog deleted on chromosome 10 contributes to phenotype transformation of fibroblasts in <d>idiopathic pulmonary fibrosis</d> via multiple pathways
199 -28449458|t|Lower expression of platelet derived growth factor is associated with better overall survival rate of patients with idiopathic nonspecific interstitial pneumonia
200 -29195901|t|Triptolide suppresses paraquat induced <d>idiopathic pulmonary fibrosis</d> by inhibiting <g>TGFB1</g>-dependent epithelial mesenchymal transition
201 -24279830|t|MicroRNA-326 regulates profibrotic functions of transforming growth factor-b in <d>pulmonary fibrosis</d>
202 -17379848|t|<g>Endothelin-1</g> <v>induces </v>alveolar epithelial-mesenchymal transition through endothelin type A receptor-<v>mediated </v><e>production </e>of <g>TGF-beta1</g>
203 -20483575|t|Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in <d>Idiopathic Pulmonary Fibrosis</d> (<d>IPF</d>)
204 -25743626|t|<g>Neutrophil elastase</g> promotes myofibroblast <d>differentiation in lung fibrosis</d>
205 -27144281|t|<g>MAP3K19</g>
206 -11463599|t|Differential mRNA expression of <g>insulin-like growth factor-1</g> splice variants in patients with <d>idiopathic pulmonary fibrosis</d> and <d>pulmonary sarcoidosis</d>
207 -17498688|t|<g>p63</g> - Key molecule in the early phase of <d>epithelial abnormality</d> in <d>idiopathic pulmonary fibrosis</d>
208 -27013092|t|Effect of Renshen Pingfei Decoction, a traditional Chinese prescription, on <d>IPF</d> <v>induced </v>by Bleomycin in rats and <r>regulation </r>of <g>TGF-b1</g>/<g>Smad3</g>
209 -24050627|t|Pathogenesis of <d>idiopathic pulmonary fibrosis</d>
210 -27317687|t|Macrophage <g>Bone Morphogenic Protein Receptor 2</g> (<g>BMPR2</g>) <u>depletion </u>in <d>Idiopathic Pulmonary Fibrosis</d> (<d>IPF</d>) and Group III Pulmonary <d>Hypertension</d>
211 -26861876|t|<u>Reduced </u><g>Ets Domain-containing Protein Elk1</g>
212 -17496059|t|Nitric oxide attenuates epithelial-mesenchymal transition in alveolar epithelial cells
213 -27909724|t|<g>HSP27</g> regulates <g>TGF-b</g> mediated lung fibroblast differentiation through the <g>Smad3</g> and <g>ERK</g> pathways
214 -24376648|t|<g>Cartilage oligomeric matrix protein</g> in <d>idiopathic pulmonary fibrosis</d>
215 -16179636|t|Negative regulation of myofibroblast differentiation by <g>PTEN</g> (Phosphatase and Tensin Homolog Deleted on chromosome 10)
216 -27583344|t|Data on <g>CUX1</g> isoforms in <d>idiopathic pulmonary fibrosis lung</d> and <d>systemic sclerosis</d> skin tissue sections
217 -21498628|t|Alveolar epithelial cells express mesenchymal proteins in patients with <d>idiopathic pulmonary fibrosis</d>
218 -26538547|t|<e>Expression </e>of <g>WNT5A</g> in <d>Idiopathic Pulmonary Fibrosis</d> and Its <r>Control </r>by <g>TGF-b</g> and <g>WNT7B</g> in Human Lung Fibroblasts
219 -29459894|t|<d>Idiopathic Pulmonary Fibrosis</d>: Aging, Mitochondrial Dysfunction, and Cellular Bioenergetics
220 -20061390|t|<g>SPARC</g> suppresses apoptosis of <d>idiopathic pulmonary fibrosis</d> fibroblasts through constitutive <v>activation </v>of <g>beta-catenin</g>
221 -27367854|t|Resveratrol-Mediated Repression and Reversion of Prostatic Myofibroblast Phenoconversion
222 -11812353|t|[The potential role of cytokines expression in <d>idiopathic pulmonary fibrosis</d>]
223 -20550546|t|Effect of an immunotoxin to <g>folate receptor beta</g> on bleomycin-induced <d>experimental pulmonary fibrosis</d>
224 -23031257|t|The hedgehog system machinery controls transforming growth factor-b-dependent myofibroblastic differentiation in humans: involvement in <d>idiopathic pulmonary fibrosis</d>
225 -26993524|t|<v>Elevated </v><e>expression </e>of <g>NEU1</g> sialidase in <d>idiopathic pulmonary fibrosis</d> <v>provokes </v>pulmonary collagen deposition, <d>lymphocytosis</d>, and <d>fibrosis</d>
226 -22684844|t|Genetic partitioning of <g>interleukin-6</g> signalling in mice dissociates <g>Stat3</g> from <g>Smad3</g>-mediated <d>lung fibrosis</d>
227 -21103368|t|Reactive oxygen species are required for maintenance and differentiation of primary lung fibroblasts in <d>idiopathic pulmonary fibrosis</d>
228 -25361680|t|<v>Upregulation </v>of <g>activin</g>-B and <g>follistatin</g> in <d>pulmonary fibrosis</d> - a translational study using human biopsies and a specific inhibitor in mouse <d>fibrosis</d> models
229 -18177235|t|Oxidant-antioxidant imbalance as a potential contributor to the progression of human <d>pulmonary fibrosis</d>
230 -1892646|t|Increased production and immunohistochemical localization of <g>transforming growth factor-beta</g> in <d>idiopathic pulmonary fibrosis</d>
231 -28060543|t|<u>Inhibition </u>of the <g>KCa3.1</g>
232 -20495078|t|<g>FGF-1</g> reverts epithelial-mesenchymal transition induced by <g>TGF-{beta}1</g> through MAPK/ERK kinase pathway
233 -19648289|t|N-acetylcysteine inhibits alveolar epithelial-mesenchymal transition
234 -24204629|t|Type V collagen induced tolerance suppresses collagen deposition, <g>TGF-b</g> and associated transcripts in <d>pulmonary fibrosis</d>
235 -11491168|t|Type II alveolar epithelial cells and interstitial fibroblasts express <g>connective tissue growth factor</g> in <d>IPF</d>
236 -19361498|t|<g>CUX1</g>/Wnt signaling regulates epithelial mesenchymal transition in EBV infected epithelial cells
237 -22923663|t|Lactic acid is elevated in <d>idiopathic pulmonary fibrosis</d> and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-b
238 -27029074|t|Preventive and therapeutic effects of thymosin b4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis
239 -19104148|t|Epithelial cell alpha3beta1 integrin links <g>beta-catenin</g> and Smad signaling to promote myofibroblast formation and <d>pulmonary fibrosis</d>
240 -22854509|t|EMT and <d>interstitial lung disease</d>: a mysterious relationship
241 -28148565|t|Pirfenidone exerts antifibrotic effects through <u>inhibition </u>of GLI transcription factors
242 -22322297|t|<g>STAT3</g>-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF
243 -21086900|t|Epithelial stem cell exhaustion in the pathogenesis of <d>idiopathic pulmonary fibrosis</d>
244 -23499373|t|FAK-related nonkinase is a multifunctional negative regulator of <d>pulmonary fibrosis</d>
245 -25252739|t|Nitrated fatty acids reverse <d>pulmonary fibrosis</d> by dedifferentiating myofibroblasts and promoting collagen uptake by alveolar macrophages
246 -23523906|t|Berberine attenuates bleomycin induced <d>pulmonary toxicity</d> and <d>fibrosis</d> via <u>suppressing </u><g>NF-kB</g> dependant <g>TGF-b</g> <v>activation:</v> a biphasic experimental study
247 -19393328|t|<g>N-acetyl-L-cysteine</g> inhibits <g>TGF-beta1</g>-induced profibrotic responses in fibroblasts
248 -28873461|t|Interleukin-17 induces human alveolar epithelial to mesenchymal cell transition via the <g>TGF-b1</g> <v>mediated </v><g>Smad2/3</g> and <g>ERK1/2</g> <v>activation.</v> <d>Idiopathic pulmonary fibrosis</d> (<d>IPF</d>) is a chronic and usually progressive <d>lung disease</d> and the epithelial-mesenchymal transition (EMT) may play an important role in the pathogenesis of <d>pulmonary fibrosis</d>
249 -28389561|t|<g>Transforming growth factor b1</g> (<g>TGFb1</g>)-induced CD44V6-<g>NOX4</g> signaling in pathogenesis of <d>idiopathic pulmonary fibrosis</d>
250 -15946381|t|<g>TGF-beta1</g> induces human alveolar epithelial to mesenchymal cell transition (EMT)
251 -17579094|t|Thalidomide prevents bleomycin-induced <d>pulmonary fibrosis</d> in mice
252 -28081703|t|Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis
253 -22394287|t|Intratracheal bleomycin causes airway remodeling and airflow obstruction in mice
254 -9163845|t|Significance of <v>elevated </v>procollagen-III-peptide and <g>transforming growth factor-beta</g> levels of bronchoalveolar lavage fluids from <d>idiopathic pulmonary fibrosis</d> patients
255 -27508042|t|<g>MiR-338</g>* targeting <g>smoothened</g> to inhibit <d>pulmonary fibrosis</d> by epithelial-mesenchymal transition
256 -20160152|t|Proteasomal regulation of <d>pulmonary fibrosis</d>
257 -26150910|t|Pleural mesothelial cells in <d>pleural and lung diseases</d>
258 -22802290|t|<d>Idiopathic pulmonary fibrosis</d>: an altered fibroblast proliferation linked to <d>cancer</d> biology
259 -23055696|t|Current and novel drug therapies for <d>idiopathic pulmonary fibrosis</d>
260 -21135509|t|Epithelium-specific deletion of <g>TGF-b</g> receptor type II protects mice from bleomycin-induced <d>pulmonary fibrosis</d>
261 -17178917|t|<g>Caveolin-1</g>: a critical regulator of <d>lung fibrosis</d> in <d>idiopathic pulmonary fibrosis</d>
262 -21659414|t|<g>Renin</g> is an angiotensin-independent profibrotic mediator: role in <d>pulmonary fibrosis</d>
263 -26474459|t|<g>Protease activated receptor-1</g> regulates macrophage-mediated cellular senescence: a risk for <d>idiopathic pulmonary fibrosis</d>
264 -19104143|t|Role for alpha3 integrin in EMT and <d>pulmonary fibrosis</d>
265 -25197006|t|Beyond <g>TGFb</g> - Novel ways to target airway and parenchymal <d>fibrosis</d>
266 -28292882|t|<g>Cthrc1</g> lowers pulmonary collagen associated with bleomycin-induced <d>fibrosis</d> and protects lung function
267 -24921217|t|Wnt coreceptor <g>Lrp5</g> is a driver of <d>idiopathic pulmonary fibrosis</d>
268 -28751023|t|<g>Lysocardiolipin acyltransferase</g> regulates <g>TGF-b</g> mediated lung fibroblast differentiation
269 -12882453|t|Cytokine profiles in <d>idiopathic pulmonary fibrosis</d> suggest an important role for <g>TGF-beta</g> and <g>IL-10</g>
270 -27476938|t|Protective Effect of Ginsenoside Rg1 on Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of <g>Caveolin-1</g> and <g>TGF-b1</g>
271 -29409529|t|The <g>JAK2</g> pathway is activated in <d>idiopathic pulmonary fibrosis</d>
272 -26268659|t|<g>CXCL9</g>
273 -28128990|t|Differing Expression of Cytokines and <d>Tumor</d>
274 -25446881|t|Sphingolipids in <d>pulmonary fibrosis</d>
275 -22106015|t|Sphingosine-1-phosphate is increased in patients with <d>idiopathic pulmonary fibrosis</d> and mediates epithelial to mesenchymal transition
276 -22661007|t|<g>miR-31</g> is a negative regulator of fibrogenesis and <d>pulmonary fibrosis</d>
277 -12947024|t|<u>Defect </u>of <g>hepatocyte growth factor</g> <l>secretion </l>by fibroblasts in <d>idiopathic pulmonary fibrosis</d>
278 -29118928|t|<g>MiR-5100</g> targets <g>TOB2</g> to drive epithelial-mesenchymal transition associated with <v>activating </v><g>smad2/3</g> in lung epithelial cells
279 -22802283|t|The impact of <g>TGF-b</g> on lung <d>fibrosis</d>: from targeting to biomarkers
280 -23436625|t|Mast cell chymase: an indispensable instrument in the pathological symphony of <d>idiopathic pulmonary fibrosis</d>? <d>Idiopathic pulmonary fibrosis</d> (<d>IPF</d>) is a chronic, progressive and fatal <d>lung disease</d> with no known etiology and treatment options
281 -29279415|t|Leucine-rich a-2 glycoprotein promotes <d>lung fibrosis</d> by modulating <g>TGF-b</g> signaling in fibroblasts
282 -20685750|t|<g>NOX4</g>/NADPH oxidase <e>expression </e>is <v>increased </v>in pulmonary fibroblasts from patients with <d>idiopathic pulmonary fibrosis</d> and mediates <g>TGFbeta1</g>-induced fibroblast differentiation into myofibroblasts
283 -28385812|t|Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts
284 -26248335|t|Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-b Induced Myofibroblast Differentiation via Prostaglandin E2
285 -24279676|t|Matrix regulation of <d>idiopathic pulmonary fibrosis</d>: the role of enzymes
286 -24811261|t|Carbon monoxide-bound hemoglobin-vesicles for the treatment of bleomycin-induced <d>pulmonary fibrosis</d>
287 -26971883|t|Sustained <g>PI3K</g>
288 -16787145|t|Pirfenidone for the treatment of <d>idiopathic pulmonary fibrosis</d>
289 -28131417|t|miR-18a-5p <u>Inhibits </u>Sub-pleural Pulmonary Fibrosis by Targeting <g>TGF-b</g>
290 -18093617|t|Pirfenidone <u>inhibits </u>the <e>expression </e>of <g>HSP47</g> in <g>TGF-beta1</g>-stimulated human lung fibroblasts
291 -16908447|t|Tissue inhibitor of metalloproteinase-3 is up-regulated by <g>transforming growth factor-beta1</g> in vitro and expressed in fibroblastic foci in vivo in <d>idiopathic pulmonary fibrosis</d>
292 -20560295|t|N-acetylcysteine <u>inhibits </u><g>TNF-alpha</g>, sTNFR, and <g>TGF-beta1</g> release by alveolar macrophages in <d>idiopathic pulmonary fibrosis</d> in vitro
293 -26249221|t|Increased Galectin-9 Concentration and Number of CD4+Foxp3high+Cells in Bronchoalveolar Lavage Fluid of Patients with <d>Cryptogenic Organizing Pneumonia</d>
294 -26192087|t|Rapamycin <v>increases </v><g>CCN2</g> <e>expression </e>of lung fibroblasts via <g>phosphoinositide 3-kinase</g>
295 -25684348|t|Transforming growth factor-b <u>inhibits </u>IQ motif containing guanosine triphosphatase <v>activating </v>protein 1 <e>expression </e>in lung fibroblasts via the nuclear factor-kB signaling pathway
296 -25533688|t|[The expressions and meanings of <g>BMP-7</g> and <g>TGF-b</g> in <d>idiopathic pulmonary fibrosis</d> and <d>idiopathic nonspecific interstitial pneumonia</d>]
297 -21169469|t|<g>Yin yang 1</g> is a novel regulator of <d>pulmonary fibrosis</d>
298 -21642472|t|Role of <d>von Hippel-Lindau</d> protein in fibroblast proliferation and <d>fibrosis</d>
299 -23492187|t|<g>X-linked inhibitor of apoptosis</g> regulates lung fibroblast resistance to Fas-mediated apoptosis
300 -22365247|t|<d>Idiopathic pulmonary fibrosis</d>: pathobiology of novel approaches to treatment
301 -27390284|t|Age-driven developmental drift in the pathogenesis of <d>idiopathic pulmonary fibrosis</d>
302 -28095470|t|Endogenous <g>Semaphorin-7A</g>
303 -15563636|t|Progressive transforming growth factor beta1-induced <d>lung fibrosis</d> is blocked by an orally active <g>ALK5</g> kinase <u>inhibitor.</u> <d>Pulmonary fibrosis</d> is characterized by chronic scar formation and deposition of extracellular matrix, resulting in <d>impaired lung function</d> and <d>respiratory failure</d>
304 -25829947|t|Human lung myofibroblast <g>TGFb1</g>-dependent <g>Smad2/3</g> signalling is Ca(2+)-dependent and <r>regulated </r>by <g>KCa3.1</g>
305 -15677772|t|Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts
306 -26138704|t|The anti-fibrotic effect of <u>inhibition </u>of <g>TGFb</g>-<g>ALK5</g> signalling in experimental <d>pulmonary fibrosis</d> in mice is attenuated in the presence of concurrent y-herpesvirus infection
307 -25557625|t|MicroRNA regulatory networks in <d>idiopathic pulmonary fibrosis</d>
308 -27941755|t|Fibroblastic foci, covered with <d>alveolar epithelia</d> exhibiting <d>epithelial-mesenchymal transition</d>, destroy <d>alveolar septa</d> by disrupting blood flow in <d>idiopathic pulmonary fibrosis</d>
309 -21166126|t|[A role for mesothelial cells in the genesis of <d>idiopathic pulmonary fibrosis</d>?]
310 -17198680|t|<e>Overproduction </e>of collagen and <u>diminished </u><g>SOCS1</g> <e>expression </e>are causally linked in fibroblasts from <d>idiopathic pulmonary fibrosis</d>
311 -28446589|t|Antifibrotic effects of <g>cyclosporine A</g> on <g>TGF-b1</g>-treated lung fibroblasts and lungs from bleomycin-treated mice: role of <g>hypoxia-inducible factor-1a</g>
312 -12055267|t|<g>TGF-beta 1</g> as an enhancer of Fas-mediated apoptosis of lung epithelial cells
313 -26207697|t|<r>Regulation </r>of 26S Proteasome Activity in <d>Pulmonary Fibrosis</d>
314 -27658114|t|Therapeutic targets in fibrotic pathways
315 -25848047|t|Compromised peroxisomes in <d>idiopathic pulmonary fibrosis</d>, a vicious cycle inducing a higher fibrotic response via <g>TGF-b</g> signaling
316 -15734789|t|<d>Lung infection</d> with gamma-herpesvirus induces progressive <d>pulmonary fibrosis</d> in Th2-biased mice
317 -25745043|t|Mode of action of nintedanib in the treatment of <d>idiopathic pulmonary fibrosis</d>
318 -23220917|t|<g>Semaphorin 7a</g>+ regulatory T cells are associated with progressive <d>idiopathic pulmonary fibrosis</d> and are implicated in transforming growth factor-b1-induced <d>pulmonary fibrosis</d>
319 -25373521|t|Mesenchymal Stem Cells Correct Inappropriate Epithelial-mesenchyme Relation in <d>Pulmonary Fibrosis</d>
320 -20671305|t|Increased expression of 5-hydroxytryptamine2A/B receptors in <d>idiopathic pulmonary fibrosis</d>: a rationale for therapeutic intervention
321 -17504233|t|Angiotensin-<g>TGF-beta</g> 1 crosstalk in human <d>idiopathic pulmonary fibrosis</d>: autocrine mechanisms in myofibroblasts and macrophages
322 -21056957|t|<v>Increased </v>deposition of chondroitin/dermatan sulfate glycosaminoglycan and <v>upregulation </v>of b1,3-glucuronosyltransferase I in <d>pulmonary fibrosis</d>
323 -19850962|t|SNAI transcription factors mediate epithelial-mesenchymal transition in <d>lung fibrosis</d>
324 -16246848|t|Proliferation of pulmonary interstitial fibroblasts is mediated by <g>transforming growth factor-beta1</g>-induced release of extracellular <g>fibroblast growth factor-2</g> and <p>phosphorylation </p>of <g>p38</g>
325 -24140943|t|Pathogenesis pathways of <d>idiopathic pulmonary fibrosis</d> in bleomycin-induced <d>lung injury</d> model in mice
326 -27279470|t|Latent cytomegalovirus infection exacerbates experimental <d>pulmonary fibrosis</d> by <v>activating </v><g>TGF-b1</g>
327 -22117501|t|Prognostic factors for <d>idiopathic pulmonary fibrosis</d>: clinical, physiologic, pathologic, and molecular aspects
328 -17391951|t|<r>Effects </r>of antifibrotic agents on <g>TGF-beta1</g>, <g>CTGF</g> and <g>IFN-gamma</g> <e>expression </e>in patients with <d>idiopathic pulmonary fibrosis</d>
329 -15857893|t|Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts
330 -24756129|t|<g>Microsomal prostaglandin E synthase-1</g> <u>deficiency </u>exacerbates <d>pulmonary fibrosis</d> induced by bleomycin in mice
331 -23517551|t|<g>Secreted protein acidic and rich in cysteine</g> (<g>SPARC</g>) is upregulated by transforming growth factor (TGF)-b and is required for <g>TGF-b</g>-induced hydrogen peroxide production in fibroblasts
332 -20566741|t|Inhibition of NF-kappaB signaling reduces virus load and gammaherpesvirus-induced <d>pulmonary fibrosis</d>
333 -27937011|t|Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on <d>pulmonary fibrosis</d> in rat <d>idiopathic pulmonary fibrosis</d> models
334 -27508041|t|<g>MiR-338</g>* suppresses fibrotic pathogenesis in <d>pulmonary fibrosis</d> through targeting <g>LPA1</g>
335 -21224216|t|Accelerated epithelial cell senescence in <d>IPF</d> and the inhibitory role of <g>SIRT6</g> in <g>TGF-b</g>-induced senescence of human bronchial epithelial cells
336 -9817168|t|<g>Transforming growth factor-beta1</g> in <d>sarcoidosis</d>
337 -29411215|t|The lncRNA <g>H19</g>
338 -26956419|t|<e>Contribution </e>of the anaphylatoxin receptors, <g>C3aR</g> and <g>C5aR</g>, to the pathogenesis of <d>pulmonary fibrosis</d>
339 -24886817|t|Corilagin attenuates aerosol bleomycin-induced experimental <d>lung injury</d>
340 -22771387|t|<g>TGF-b1</g> induces <g>tissue factor</g> expression in human lung fibroblasts in a <g>PI3K</g>/<g>JNK</g>/<g>Akt</g>-dependent and <g>AP-1</g>-dependent manner
341 -12837171|t|[Potential role of cytokines in <d>idiopathic pulmonary fibrosis</d>]
342 -24300094|t|Protective role of andrographolide in bleomycin-induced <d>pulmonary fibrosis</d> in mice
343 -23896962|t|Epithelial-mesenchymal transition in chronic <d>hypersensitivity pneumonitis</d>
344 -22406480|t|<g>Serpin B4</g> isoform overexpression is associated with aberrant epithelial proliferation and <d>lung cancer</d> in <d>idiopathic pulmonary fibrosis</d>
345 -28469072|t|Uncoupling of the profibrotic and hemostatic effects of <g>thrombin</g> in <d>lung fibrosis</d>
346 -10931794|t|Interstitial <d>fibrosis</d> and growth factors
347 -17934117|t|Molecular targets in <d>pulmonary fibrosis</d>: the myofibroblast in focus
348 -27107963|t|Immunomodulation by mesenchymal stem cells in treating human <d>autoimmune disease-associated lung fibrosis</d>
349 -21475793|t|<u>Reduced </u>transcription of the <g>Smad4</g> gene during <d>pulmonary carcinogenesis</d> in <d>idiopathic pulmonary fibrosis</d>
350 -24641440|t|Intrinsic defence capacity and therapeutic potential of natriuretic peptides in <d>pulmonary hypertension</d> associated with <d>lung fibrosis</d>
351 -21212602|t|<u>Blockade </u>of the Wnt/b-catenin pathway attenuates bleomycin-induced <d>pulmonary fibrosis</d>
352 -20061443|t|Curcumin inhibits <d>fibrosis</d>-related effects in <d>IPF</d> fibroblasts and in mice following bleomycin-induced <d>lung injury</d>
353 -19701206|t|<g>NADPH oxidase-4</g> mediates myofibroblast activation and fibrogenic responses to <d>lung injury</d>
354 -25032514|t|Anti-fibrotic Role of aB-crystallin Inhibition in Pleural and Subpleural <d>Fibrosis</d>
355 -26231702|t|Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of <d>lung inflammation</d> and <d>fibrosis</d>
356 -25182202|t|Reviews and prospectives of signaling pathway analysis in <d>idiopathic pulmonary fibrosis</d>
357 -23376055|t|Roles of p38 MAPK and <g>JNK</g> in <g>TGF-b1</g>-induced human alveolar epithelial to mesenchymal transition
358 -17363768|t|Control of virus reactivation arrests pulmonary herpesvirus-induced <d>fibrosis</d> in IFN-gamma receptor-<u>deficient </u>mice
359 -12243323|t|BALF N-acetylglucosaminidase and <g>beta-galactosidase</g> activities in <d>idiopathic pulmonary fibrosis</d>
360 -22173045|t|Predisposition for disrepair in the aged lung
361 -24088250|t|Possible involvement of pirfenidone metabolites in the antifibrotic action of a therapy for <d>idiopathic pulmonary fibrosis</d>
362 -23006535|t|N-acetylcysteine <u>downregulation </u>of <g>lysyl oxidase</g> activity alleviating bleomycin-induced <d>pulmonary fibrosis</d> in rats
363 -28259823|t|Evaluation of permeability alteration and epithelial-mesenchymal transition induced by <g>transforming growth factor-b1</g> in A549, NCI-H441, and Calu-3 cells: Development of an in vitro model of respiratory epithelial cells in <d>idiopathic pulmonary fibrosis</d>
364 -29046395|t|Epithelial contribution to the pro-fibrotic stiff microenvironment and myofibroblast population in lung <d>fibrosis</d>
365 -22241478|t|Interactions between <g>b-catenin</g> and <g>transforming growth factor-b</g> signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (<g>CREB)-binding protein</g> (<g>CBP</g>)
366 -15281432|t|BAL cytokine profile in different <d>interstitial lung diseases</d>: a focus on <d>systemic sclerosis</d>
367 -22900087|t|<g>Syndecan-2</g> is a novel target of <g>insulin-like growth factor binding protein-3</g> and is <v>over-expressed </v>in <d>fibrosis</d>
368 -26599507|t|Membrane-anchored <g>Serine Protease</g> <g>Matriptase</g>
369 -21278261|t|Interplay between <g>RAGE</g>, <g>CD44</g>, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells
370 -26545872|t|Antifibrotic properties of receptor for advanced glycation end products in <d>idiopathic pulmonary fibrosis</d>
371 -25496490|t|Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with <d>idiopathic pulmonary fibrosis</d>
372 -24307592|t|The small heat-shock protein aB-crystallin is essential for the nuclear <l>localization </l>of <g>Smad4</g>: impact on <d>pulmonary fibrosis</d>
373 -29144435|t|Dysregulated Collagen Homeostasis by Matrix Stiffening and <g>TGF-b1</g> in Fibroblasts from <d>Idiopathic Pulmonary Fibrosis</d>
374 -15564021|t|Medical treatment for <d>pulmonary fibrosis</d>: current trends, concepts, and prospects
375 -24669082|t|Ambroxol hydrochloride in the management of <d>idiopathic pulmonary fibrosis</d>: Clinical trials are the need of the hour
376 -27467922|t|Combined <u>inhibition </u>of <g>TGFb</g> and PDGF signaling attenuates radiation-induced <d>pulmonary fibrosis</d>
377 -25244495|t|Diagnostic Values For Club Cell Secretory Protein (<g>CC16</g>) in Serum of Patients of Combined Pulmonary Fibrosis and Emphysema
378 -26098610|t|<e>Effects </e>of <g>thymosin b4</g> and its N-terminal fragment Ac-SDKP on <g>TGF-b</g>-treated human lung fibroblasts and in the mouse model of bleomycin-induced <d>lung fibrosis</d>
379 -21871427|t|Matrix metalloproteinase 3 is a mediator of <d>pulmonary fibrosis</d>
380 -23977848|t|An <u>inhibitor </u>of NADPH oxidase-4 attenuates established <d>pulmonary fibrosis</d> in a <d>rodent disease</d> model
381 -23344525|t|TGF-b1 T869C polymorphism may affect susceptibility to <d>idiopathic pulmonary fibrosis</d> and disease severity
382 -16573560|t|<g>Th1</g>/Th2 cytokine gene polymorphisms in patients with <d>idiopathic pulmonary fibrosis</d>
383 -21984893|t|<u>Inhibition </u>of <g>PI3K</g> prevents the proliferation and differentiation of human lung fibroblasts into myofibroblasts: the role of class I P110 isoforms
384 -21502778|t|<r>Effects </r>of doxycycline on <e>production </e>of growth factors and matrix metalloproteinases in <d>pulmonary fibrosis</d>
385 -26523510|t|Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties
386 -8678788|t|Cytokines in human <d>lung fibrosis</d>
387 -28662409|t|Human placental mesenchymal stem cells of fetal origins-alleviated <d>inflammation</d> and <d>fibrosis</d> by attenuating <g>MyD88</g> signaling in bleomycin-induced <d>pulmonary fibrosis</d> mice
388 -12475802|t|Roles for <g>insulin-like growth factor I</g> and <g>transforming growth factor-beta</g> in <d>fibrotic lung disease</d>
389 -27310652|t|<e>Expression </e>of <g>RXFP1</g>
390 -23583521|t|Role of <g>caveolin-1</g> in <d>fibrotic diseases</d>
391 -28810065|t|Olodaterol shows anti-fibrotic efficacy in in vitro and in vivo models of <d>pulmonary fibrosis</d>
392 -26072676|t|Novel Mechanisms for the Antifibrotic Action of Nintedanib
393 -21864521|t|Plasma <g>CCN2</g> (connective tissue growth factor; <g>CTGF</g>) is a potential biomarker in <d>idiopathic pulmonary fibrosis</d> (<d>IPF</d>)
394 -28613983|t|Azithromycin attenuates myofibroblast differentiation and lung <d>fibrosis</d> development through <d>proteasomal degradation</d> of <g>NOX4</g>
395 -27836973|t|Transforming Growth Factor (TGF)-b Promotes de Novo Serine Synthesis for Collagen <e>Production.</e> <g>TGF-b</g> <v>promotes </v>excessive collagen deposition in <d>fibrotic diseases</d> such as <d>idiopathic pulmonary fibrosis</d> (<d>IPF</d>)
396 -23021430|t|Association between cytokine removal by polymyxin B hemoperfusion and improved pulmonary oxygenation in patients with acute exacerbation of <d>idiopathic pulmonary fibrosis</d>
397 -24958208|t|Crosstalk between <g>TGF-b1</g> and complement activation augments epithelial <d>injury in pulmonary fibrosis</d>
398 -25842923|t|[The morphology and molecular bases of damage to the stem cell niche of respiratory acini in <d>idiopathic interstitial pneumonias</d>]
399 -28577568|t|Pirfenidone inhibits myofibroblast differentiation and <d>lung fibrosis</d> development during insufficient mitophagy
400 -20176803|t|Bleomycin and <g>IL-1beta</g>-mediated <d>pulmonary fibrosis</d> is <g>IL-17A</g> dependent
401 -15681824|t|Insulin-like growth factor binding proteins 3 and 5 are <v>overexpressed </v>in <d>idiopathic pulmonary fibrosis</d> and contribute to extracellular matrix deposition
402 -19381013|t|<g>VEGF</g> ameliorates pulmonary <d>hypertension</d> through inhibition of endothelial apoptosis in experimental lung <d>fibrosis</d> in rats
403 -23986222|t|Rapamycin regulates connective tissue growth factor expression of lung epithelial cells via phosphoinositide 3-kinase
404 -23459460|t|miR-199a-5p Is <v>upregulated </v>during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting <g>caveolin-1</g>
405 -23434591|t|Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental <d>pulmonary fibrosis</d>
406 -24853416|t|Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during <d>idiopathic pulmonary fibrosis</d>
407 -8918367|t|Differential <e>expression </e>of alpha E beta 7 integrins on bronchoalveolar lavage T lymphocyte subsets: <r>regulation </r>by alpha 4 beta 1-integrin crosslinking and <g>TGF-beta</g>
408 -11394717|t|<v>Increased </v><g>TGF-beta1</g> in the lungs of asbestos-exposed rats and mice: <u>reduced </u><e>expression </e>in <g>TNF-alpha</g> receptor knockout mice
409 -18795102|t|Fibrotic myofibroblasts manifest genome-wide derangements of translational control
410 -17982242|t|<g>Transforming growth factor beta1</g> induces epithelial-to-mesenchymal transition of A549 cells
411 -22434388|t|<r>Regulation </r>of <g>TGF-b</g> storage and activation in the human <d>idiopathic pulmonary fibrosis lung</d>
412 -26216407|t|The anti-fibrotic effects of microRNA-153 by <r>targeting </r><g>TGFBR-2</g> in <d>pulmonary fibrosis</d>
413 -11306432|t|<d>Microsatellite instability</d> in transforming growth factor-beta 1 type II receptor gene in alveolar lining epithelial cells of <d>idiopathic pulmonary fibrosis</d>
414 -24953558|t|miR-92a <r>regulates </r><g>TGF-b1</g>-<v>induced </v><g>WISP1</g> <e>expression </e>in <d>pulmonary fibrosis</d>
415 -29019702|t|<u>Inhibition </u>of <g>PHGDH</g>
416 -8680382|t|The role of cytokines in human <d>lung fibrosis</d>
417 -20693406|t|The Epstein-Barr virus latent membrane protein 1 and transforming growth factor--b1 synergistically induce epithelial--mesenchymal transition in lung epithelial cells
418 -12851645|t|Significant involvement of <g>CCL2</g> (<g>MCP-1</g>) in inflammatory disorders of the lung
419 -17631612|t|<g>TGF-beta</g>-induced EMT: mechanisms and implications for <d>fibrotic lung disease</d>
420 -22694981|t|Pirfenidone <u>inhibits </u><g>TGF-b1</g>-induced <e>over-expression </e>of collagen type I and <d>heat shock</d> protein 47 in A549 cells
421 -23565148|t|Bleomycin induces molecular changes directly relevant to <d>idiopathic pulmonary fibrosis</d>: a model for "active" disease
422 -19487460|t|<u>Defective </u>histone acetylation is <r>responsible </r>for the <u>diminished </u><e>expression </e>of <g>cyclooxygenase 2</g> in <d>idiopathic pulmonary fibrosis</d>
423 -24879051|t|y-Herpes virus-68, but not Pseudomonas aeruginosa or influenza A (H1N1), exacerbates <d>established murine lung fibrosis</d>
424 -11776068|t|The potential <r>role </r>of PDGF, <g>IGF-1</g>, <g>TGF-beta</g> <e>expression </e>in <d>idiopathic pulmonary fibrosis</d>
425 -20395557|t|Inhibition and role of <g>let-7d</g> in <d>idiopathic pulmonary fibrosis</d>
426 -19411308|t|Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to <g>TGF-beta1</g> in vitro
427 -26709222|t|Association of HLA and cytokine gene polymorphisms with <d>idiopathic pulmonary fibrosis</d>
428 -15298857|t|<g>Connective tissue growth factor</g> <e>expression </e>and <v>induction </v>by <g>transforming growth factor-beta</g> is <u>abrogated </u>by simvastatin via a Rho signaling mechanism
429 -28573228|t|MOXIBUSTION HAS A POSITIVE EFFECT ON PULMONARY FIBROSIS: AN ALTERNATIVE APPROACH
430 -28667660|t|Signaling pathways and their miRNA regulators involved in the etiopathology of <d>idiopathic pulmonary fibrosis</d> (<d>IPF</d>) and <d>hypersensitivity pneumonitis</d> (<d>HP</d>)
431 -25660181|t|Sustained Activation of <g>Toll-Like Receptor 9</g>
432 -20643828|t|<g>miR-21</g> mediates fibrogenic activation of pulmonary fibroblasts and lung <d>fibrosis</d>
433 -9512902|t|Molecular pathogenesis of <d>interstitial pneumonitis</d> with <g>TNF-alpha</g> transgenic mice
434 -19597127|t|<g>Transcription factor GATA-6</g> is <e>expressed </e>in quiescent myofibroblasts in <d>idiopathic pulmonary fibrosis</d>
435 -26675886|t|Inhibitory effects of amines from Citrus reticulata on bleomycin-induced <d>pulmonary fibrosis</d> in rats
436 -16837501|t|Thalidomide <u>reduces </u><g>IL-18</g>, <g>IL-8</g> and <g>TNF-alpha</g> <l>release </l>from alveolar macrophages in <d>interstitial lung disease</d>
437 -28816543|t|MiR-541-5p <r>regulates </r><d>lung fibrosis</d> by <r>targeting </r>cyclic nucleotide phosphodiesterase 1A
438 -20952439|t|The pathogenesis of <d>idiopathic pulmonary fibrosis</d>
439 -26093215|t|Effect of glycosides based standardized fenugreek seed extract in bleomycin-induced <d>pulmonary fibrosis</d> in rats: Decisive role of <g>Bax</g>, <g>Nrf2</g>, <g>NF-kB</g>, <g>Muc5ac</g>, <g>TNF-a</g> and <g>IL-1b</g>
440 -22189082|t|Participation of miR-200 in <d>pulmonary fibrosis</d>
441 -26370615|t|The Anti-fibrotic Effects and Mechanisms of MicroRNA-486-5p in <d>Pulmonary Fibrosis</d>
442 -28754682|t|<d>Autoimmunity</d> to Vimentin Is Associated with Outcomes of Patients with <d>Idiopathic Pulmonary Fibrosis</d>
443 -8630262|t|<g>TGF-beta 1</g>, but not <g>TGF-beta 2</g> or <g>TGF-beta 3</g>, is differentially present in epithelial cells of advanced <d>pulmonary fibrosis</d>: an immunohistochemical study
444 -29125826|t|Lysyl oxidases <r>regulate </r>fibrillar collagen remodelling in idiopathic pulmonary fibrosis
445 -25725128|t|Discovery and validation of extracellular/circulating microRNAs during <d>idiopathic pulmonary fibrosis disease</d> progression
446 -23380438|t|Recombinant human <g>serum amyloid P</g> in healthy volunteers and patients with <d>pulmonary fibrosis</d>
447 -17975199|t|<g>Gremlin</g>-mediated decrease in bone morphogenetic protein signaling promotes <d>pulmonary fibrosis</d>
448 -25199049|t|<v>Increased </v><e>expression </e>of <g>protease nexin-1</g> in fibroblasts during <d>idiopathic pulmonary fibrosis</d> <r>regulates </r><g>thrombin</g> activity and <g>fibronectin</g> <e>expression.</e> <d>Idiopathic pulmonary fibrosis</d> (<d>IPF</d>) is a chronic <d>diffuse lung disease</d> characterized by an accumulation of excess fibrous material in the lung
449 -27746237|t|The role of microRNA-155/liver X receptor pathway in experimental and <d>idiopathic pulmonary fibrosis</d>
450 -18395486|t|Hyper-responsiveness of <d>IPF</d>/<d>UIP</d> fibroblasts: interplay between <g>TGFbeta1</g>, <g>IL-13</g> and <g>CCL2</g>
451 -22088447|t|<d>Idiopathic pulmonary fibrosis</d> in relation to gene polymorphisms of <g>transforming growth factor-b1</g> and <g>plasminogen activator inhibitor 1</g>
452 -11502094|t|<g>TNF-alpha</g>, PDGF, and <g>TGF-beta(1)</g> <e>expression </e>by primary mouse bronchiolar-alveolar epithelial and mesenchymal cells: <g>tnf-alpha</g> induces <g>TGF-beta(1)</g>
453 -25331544|t|<g>Transforming Growth Factor Beta 1</g>
454 -28678431|t|Epithelial-to-mesenchymal transition and its role in <g>EGFR</g>-mutant <d>lung adenocarcinoma</d> and <d>idiopathic pulmonary fibrosis</d>
455 -21882188|t|<g>Cysteine-rich protein 1</g> is regulated by <g>transforming growth factor-b1</g> and expressed in lung <d>fibrosis</d>